ArticleCell host & microbe2020
Surveillance of European Domestic Pig Populations Identifies an Emerging Reservoir of Potentially Zoonotic Swine Influenza A Viruses.
Article in Cell host & microbe, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
92 citing papers in PubMed, 144 citations in OpenAlex.
- Detecting swine influenza A virus during fattening and at slaughter: implications for monitoring strategies in fattening herds.Porcine health management · 2026Article
- Perspective on human diagnostic and national reference laboratory preparedness for zoonotic influenza in Europe.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026Article
- Host-Directed Antiviral Strategies Against Influenza Viruses: Host Targets, Multi-Omics Approaches and AI-Assisted Discovery.Veterinary sciences · 2026Review
- Multiplex serological profiling reveals diverse avian and mammalian influenza A virus exposure in swine.iScience · 2026Article
- Epidemiology of Influenza A virus in Swiss pig herds: subclinical circulation and associated risk factors.Porcine health management · 2026Article
- Genetic diversity and circulation of influenza A viruses in Italian pig farms: insights from surveillance and vaccination.Porcine health management · 2026Article
- Exploring the functional microbiome of pigs within the porcine respiratory disease complex: viral-bacterial co-infections and virulence factor profiling.Microbiology spectrum · 2026Article
- Diverse genomic landscape of swine influenza A virus in England (2014-2021).Microbial genomics · 2026Article
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- Swine Influenza Virus Introduction in Pig Farms: A Semi-Quantitative Risk Assessment in Northern Italy.Animals : an open access journal from MDPI · 2026Article
- Evolution, spread and impact of highly pathogenic H5 avian influenza A viruses.Nature reviews. Microbiology · 2026Review
- High serological barriers may contribute to restricted Influenza-A-virus transmission between pigs and humans.One health (Amsterdam, Netherlands) · 2025Article
- Seasonal Influenza Vaccine 2021/2022 Provides Limited Cross Reactivity Against Contemporary Swine Influenza A Virus Strains in Spain.Influenza and other respiratory viruses · 2025Article
- Rapid surge of reassortant A(H1N1) influenza viruses in Danish swine and their zoonotic potential.Emerging microbes & infections · 2025Article
- From North to South: transmission dynamics of H1N1pdm09 swine influenza A viruses in Italy.The Journal of general virology · 2025Article
- Diagnostic performance of ELISA kits and expanded antigen panels for hemagglutination inhibition assays in pig herds enzootically infected with porcine Influenza A viruses.Porcine health management · 2025Article
- Continuous evolution of Eurasian avian-like H1N1 swine influenza viruses with pdm/09-derived internal genes enhances pathogenicity in mice.Journal of virology · 2025Article
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- Article
- Can Oral Fluids Replace Nasal Swabs in Swine Influenza A Virus (swIAV) PCR Diagnostics?Pathogens (Basel, Switzerland) · 2025Article
32 more citing papers are in PubMed but not listed here.
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Authors and funding
22 authors at 8 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Swine influenza A viruses (swIAVs) can play a crucial role in the generation of new human pandemic viruses. In this study, in-depth passive surveillance comprising nearly 2,500 European swine holdings and more than 18,000 individual samples identified a year-round presence of up to four major swIAV lineages on more than 50% of farms surveilled. Phylogenetic analyses show that intensive reassortment with human pandemic A(H1N1)/2009 (H1pdm) virus produced an expanding and novel repertoire of at least 31 distinct swIAV genotypes and 12 distinct hemagglutinin/neuraminidase combinations with largely unknown consequences for virulence and host tropism. Several viral isolates were resistant to the human antiviral MxA protein, a prerequisite for zoonotic transmission and stable introduction into human populations. A pronounced antigenic variation was noted in swIAV, and several H1pdm lineages antigenically distinct from current seasonal human H1pdm co-circulate in swine. Thus, European swine populations represent reservoirs for emerging IAV strains with zoonotic and, possibly, pre-pandemic potential.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.