Evidence map›Paper›PMID 32721213›Full record

ArticleJournal of child and adolescent psychopharmacology2020

Greater Dynamic and Lower Static Functional Brain Connectivity Prospectively Predict Placebo Response in Pediatric Generalized Anxiety Disorder.

Lu Lu, Hailong Li, Jeffrey A Mills, Heidi Schroeder, Sarah A Mossman, Sara T Varney, Kim M Cecil, Xiaoqi Huang, Qiyong Gong, Amir Levine and 3 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of child and adolescent psychopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02818751 (Neurofunctional Predictors of Escitalopram Treatment Response in Adolescents With Anxiety), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02818751 nacompletednot on this map

Neurofunctional Predictors of Escitalopram Treatment Response in Adolescents With Anxiety

TypeinterventionalSponsorUniversity of CincinnatiRan2015 to 2020Enrolled84ConditionsAnxietyArmsEscitalopram, Placebo
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Acute neurofunctional effects of escitalopram during emotional processing in pediatric anxiety: a double-blind, placebo-controlled trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lu LuDepartment of Radiology, Huaxi MR Research Center (HMRRC), West China Hospital of Sichuan University, Chengdu, China.
Hailong LiDepartment of Radiology, Huaxi MR Research Center (HMRRC), West China Hospital of Sichuan University, Chengdu, China.
Jeffrey A MillsDepartment of Economics, Lindner College of Business, University of Cincinnati, Cincinnati, Ohio, USA.
Heidi SchroederDepartment of Psychiatry, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Sarah A MossmanDepartment of Psychiatry, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Sara T VarneyDepartment of Psychiatry, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Kim M CecilDepartment of Radiology, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Xiaoqi HuangDepartment of Radiology, Huaxi MR Research Center (HMRRC), West China Hospital of Sichuan University, Chengdu, China.
Qiyong GongDepartment of Radiology, Huaxi MR Research Center (HMRRC), West China Hospital of Sichuan University, Chengdu, China.
Amir LevineDepartment of Psychiatry, Columbia University and New York State Psychiatric Institute, New York City, New York, USA.
Melissa P DelBelloDepartment of Psychiatry, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
John A SweenyDepartment of Radiology, Huaxi MR Research Center (HMRRC), West China Hospital of Sichuan University, Chengdu, China.
Jeffrey R StrawnDepartment of Psychiatry, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.

Funding

Internalizing Behaviors and Neuroimaging Outcomes: Impact of PBDE and PFC ExposuresR01ES027224 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI CECIL, KIM M, YOLTON, KIMBERLY · 2016 to 2020
$3.0M
Estracellular Vesicles as Non-Invasive Predictors of Antidepressant Outcomes in Pediatric AnxietyR01HD098757 · NICHD · UNIVERSITY OF CINCINNATI · PI STRAWN, JEFFREY ROBERT · 2019 to 2024
$2.4M
Neurofunctional Predictors of Treatment Response in Adolescents with GADK23MH106037 · NIMH · UNIVERSITY OF CINCINNATI · PI STRAWN, JEFFREY ROBERT · 2014 to 2017
$745k
NICHD NIH HHS R01 HD098757NIEHS NIH HHS R01 ES027224NIMH NIH HHS K23 MH106037
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anxiety DisordersPlacebo EffectAdolescentAmygdalaBrainFemaleGyrus CinguliHumansMagnetic Resonance ImagingMaleParietal LobePrefrontal Cortexanxiety disorderfunctional connectivityneuroimagingplacebo

Identifiers

PMID32721213
PMCPMC7864114

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.