Evidence map›Paper›PMID 32721106›Full record

ArticleJournal of applied clinical medical physics2020

Development of a method to create uniform phantoms for task-based assessment of CT image quality.

Juliane Conzelmann, Felix Benjamin Schwarz, Bernd Hamm, Michael Scheel, Paul Jahnke

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Juliane ConzelmannDepartment of Radiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
Felix Benjamin SchwarzDepartment of Radiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
Bernd HammDepartment of Radiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
Michael ScheelDepartment of Neuroradiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
Paul JahnkeDepartment of Radiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.ORCID https://orcid.org/0000-0003-2039-6316

Funding

Bundesministerium fuer Wirtschaft und Energie 03EFHBE093
6 · The paper itself

Abstract

purposeTo develop a customized method to produce uniform phantoms for task-based assessment of CT image quality.

methodsContrasts between polymethyl methacrylate (PMMA) and fructose solutions of different concentrations (240, 250, 260, 280, 290, 300, 310, 320, 330, and 340 mg/mL) were calculated. A phantom was produced by laser cutting PMMA slabs to the shape of a patient's neck. An opening of 10 mm diameter was cut into the left parapharyngeal space. An angioplasty balloon was inserted and filled with the fructose solutions to simulate low-contrast lesions. The phantom was scanned with six tube currents. Images were reconstructed with filtered back projection (FBP) and adaptive iterative dose reduction 3D (AIDR 3D). Calculated and measured contrasts were compared. The phantom was evaluated in a detectability experiment using images with 4 and 20 HU lesion contrast.

resultsLow-contrast lesions of 4, 9, 11, 13, 18, 20, 24, 30, 35, and 37 HU contrast were simulated. Calculated and measured contrasts correlated excellently (r = 0.998; 95% confidence interval: 0.991 to 1). The mean ± SD difference was 0.41 ± 2.32 HU (P < 0.0001). Detection accuracy and reader confidence were 62.9 ± 18.2% and 1.58 ± 0.68 for 4 HU lesion contrast and 99.6 ± 1.3% and 4.27 ± 0.92 for 20 HU lesion contrast (P < 0.0001), confirming that the method produced lesions at the threshold of detectability.

conclusionA cost-effective and flexible approach was developed to create uniform phantoms with low-contrast signals. The method should facilitate access to customized phantoms for task-based image quality assessment.

Indexed as

AlgorithmsTomography, X-Ray ComputedHumansPhantoms, ImagingRadiation DosageRadiographic Image Interpretation, Computer-Assistedcontrast sensitivityimagingphantomstomographyx-ray computed

Identifiers

PMID32721106
PMCPMC7497917

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.