Evidence map›Paper›PMID 32720890›Full record

ArticleThe Journal of general virology2020

Multiple novel non-canonically transcribed sub-genomic mRNAs produced by avian coronavirus infectious bronchitis virus.

Sarah Keep, Michael S Oade, Filip Lidzbarski-Silvestre, Kirsten Bentley, Phoebe Stevenson-Leggett, Graham L Freimanis, Chandana Tennakoon, Nicholas Sanderson, John A Hammond, Richard C Jones and 2 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of general virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Sarah KeepThe Pirbright Institute, Ash Road, Woking, GU24 0NF, UK.
Michael S OadeThe Pirbright Institute, Ash Road, Woking, GU24 0NF, UK.
Filip Lidzbarski-SilvestreThe Pirbright Institute, Ash Road, Woking, GU24 0NF, UK.
Kirsten BentleyThe Pirbright Institute, Ash Road, Woking, GU24 0NF, UK.
Phoebe Stevenson-LeggettThe Pirbright Institute, Ash Road, Woking, GU24 0NF, UK.
Graham L FreimanisThe Pirbright Institute, Ash Road, Woking, GU24 0NF, UK.
Chandana TennakoonThe Pirbright Institute, Ash Road, Woking, GU24 0NF, UK.
Nicholas SandersonThe Pirbright Institute, Ash Road, Woking, GU24 0NF, UK.
John A HammondThe Pirbright Institute, Ash Road, Woking, GU24 0NF, UK.
Richard C JonesSchool of Veterinary Science, University of Liverpool, Neston, UK.
Paul BrittonThe Pirbright Institute, Ash Road, Woking, GU24 0NF, UK.
Erica BickertonThe Pirbright Institute, Ash Road, Woking, GU24 0NF, UK.
The Pirbright Institute · GBUniversity of Liverpool · GB

Funding

Biotechnology and Biological Sciences Research Council BBS/E/I/00007034Biotechnology and Biological Sciences Research Council BBS/E/I/00007037Biotechnology and Biological Sciences Research Council BBS/E/I/00007039
6 · The paper itself

Abstract

Coronavirus sub-genomic mRNA (sgmRNA) synthesis occurs via a process of discontinuous transcription involving complementary transcription regulatory sequences (TRSs), one (TRS-L) encompassing the leader sequence of the 5' untranslated region (UTR), and the other upstream of each structural and accessory gene (TRS-B). Several coronaviruses have an ORF located between the N gene and the 3'-UTR, an area previously thought to be non-coding in the

Indexed as

5' Untranslated RegionsAnimalsBase SequenceCell LineChickensChlorocebus aethiopsCoronavirus InfectionsInfectious bronchitis virusOpen Reading FramesPoultry DiseasesRegulatory Sequences, Nucleic AcidRNA, MessengerRNA, ViralTranscription, GeneticVero CellsViral Proteins5' Untranslated RegionsRNA, MessengerRNA, ViralViral ProteinscoronavirusIBVRNA synthesissub-genomic mRNAtranscription

Identifiers

PMID32720890
PMCPMC7660457
OpenAlexW3045852368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.