Evidence map›Paper›PMID 32720542›Full record

ArticleDrug delivery2020

A theoretical mathematical model for assessing diclofenac release from chitosan-based formulations.

Manuela Maria Iftime, Daniel Lucian Dobreci, Stefan Andrei Irimiciuc, Maricel Agop, Tudor Petrescu, Bogdan Doroftei

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Manuela Maria IftimePetru Poni Institute of Macromolecular Chemistry, Romanian Academy of Sciences, Iasi, Romania.
Daniel Lucian DobreciDepartment of Physical and Occupational Therapy, Vasile Alecsandri University of Bacau, Bacău, Romania.
Stefan Andrei IrimiciucPlasma and Radiation Physics, National Institute for Laser, Bucharest, Romania.
Maricel AgopDepartment of Structural Mechanics, "Gh. Asachi" Technical University of Iasi, Iasi, Romania.
Tudor PetrescuDepartment of Physics, "Gh. Asachi" Technical University of Iasi, Iasi, Romania.
Bogdan DorofteiOrigyn Fertility Center, Clinical Hospital of Obstetrics and Gynaecology, "Grigore T. Popa" University of Medicine and Pharmacy, Iași, Romania.
Gheorghe Asachi Technical University of Iași · ROGrigore T. Popa University of Medicine and Pharmacy · RONational Institute for Laser Plasma and Radiation Physics · RORomanian Academy · ROUniversity of Bacău · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The paper reports a new mathematical model for understanding the mechanism delivery from drug release systems. To do this, two drug release systems based on chitosan and diclofenac sodium salt as a drug model, were prepared by in situ hydrogelation in the presence of salicylaldehyde. The morphology of the systems was analyzed by scanning electron microscopy and polarized light microscopy and the drug release was

Indexed as

Drug LiberationModels, TheoreticalAldehydesAnti-Inflammatory Agents, Non-SteroidalChemistry, PharmaceuticalChitosanDelayed-Action PreparationsDiclofenacDrug CompoundingDrug Delivery SystemsMicroscopy, Electron, ScanningModels, BiologicalAldehydesAnti-Inflammatory Agents, Non-SteroidalChitosanDelayed-Action PreparationsDiclofenacsalicylaldehydechitosandiclofenacdrug release mechanismMultifractal model

Identifiers

PMID32720542
PMCPMC7470131
OpenAlexW3045730098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.