Evidence map›Paper›PMID 32720541›Full record

ArticleThe Journal of international medical research2020

Diagnostic value of miR-155 for acute lung injury/acute respiratory distress syndrome in patients with sepsis.

Zhou-Feng Wang, Yu-Min Yang, Heng Fan

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

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  8. Preventive Effect of the Total Polyphenols fromInternational journal of molecular sciences · 2024
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  9. The preventative effects ofFrontiers in microbiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zhou-Feng WangDepartment of Respiratory and Critical Care, Ningbo First Hospital Longshan Hospital Medical and Health Group, Ningbo, Zhejiang Province, P. R. China.
Yu-Min YangDepartment of Intensive Care Unit, Ningbo First Hospital, Ningbo, Zhejiang Province, P. R. China.
Heng FanDepartment of Intensive Care Unit, Ningbo First Hospital, Ningbo, Zhejiang Province, P. R. China.ORCID https://orcid.org/0000-0003-4519-1130
Ningbo First Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to investigate the diagnostic value of microRNA-155 (miR-155) for acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) in patients with sepsis.

methodsIn this prospective study, we used Spearman correlation analysis to investigate relationships between miR-155 expression and inflammatory factors, oxygenation ratio (PaO

resultsIn total, 156 patients with sepsis were enrolled in our study, of which 41 had ALI and 32 had ARDS. miR-155 expression in plasma of patients with sepsis and ALI/ARDS was significantly higher than that of patients with sepsis but no ALI/ARDS. The miR-155 level in patients with sepsis and ALI/ARDS was positively correlated with interleukin (IL)-1β and tumor necrosis factor (TNF)-α levels and ALI/ARDS score, but negatively correlated with PaO

conclusionmiR-155 is highly expressed in plasma of patients with septic ALI/ARDS; it is positively correlated with lung function and can be used for early diagnosis.

Indexed as

Acute Lung InjuryMicroRNAsRespiratory Distress SyndromeSepsisHumansProspective StudiesMicroRNAsMIRN155 microRNA, humanacute lung injuryacute respiratory distress syndromemiR-155PaO2/FiO2 ratioprognosissepsis

Identifiers

PMID32720541
PMCPMC7388133
OpenAlexW3046124929

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.