SynthesisInternational journal of colorectal disease2020

Relationship between metformin therapy and risk of colorectal cancer in patients with diabetes mellitus: a meta-analysis.

What moved togetherboth groups pooled, not the treatment’s effect

Correlation, not cause

−12%−17% to −6%

Bigger than 4 in 10 for adverse events & safety

As reported

RR 0.884, 95% CI 0.83–0.94

the abstract, start to end

… in diabetic patients (adjusted RR = 0.884, 95%CI = 0.829-0.943), and …

← favours treatmentfavours comparator →

could be chance

Adverse events & safety

RR 0.8840.83–0.94

MetforminAdverse events & safety

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