Evidence map›Paper›PMID 32720130›Full record

ArticleInfection2020

Duration of posaconazole therapy for Aspergillus fumigatus osteomyelitis dictated by serial monitoring of 1,3-beta-D glucan.

James B Doub, Poonam Mathur

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. A Rare Case of MandibularDentistry journal · 2022
    Article
  2. Isavuconazole in the Treatment ofAntibiotics (Basel, Switzerland) · 2022
    Review
  3. Osseous Infections Caused byDiagnostics (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

James B DoubDivision of Infectious Diseases, University of Maryland School of Medicine, 725 west Lombard Street, Baltimore, MD, 21201, USA. Jdoub@ihv.umaryland.edu.
Poonam MathurDivision of Infectious Diseases, University of Maryland School of Medicine, 725 west Lombard Street, Baltimore, MD, 21201, USA.
University of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we present a case of an immunocompetent 37-year old male who developed Aspergillus fumigatus osteomyelitis 16 years after extensive chest wall reconstructive surgery for Ewing sarcoma. His treatment course was complicated by a severe adverse drug reaction to voriconazole, requiring the use of oral posaconazole therapy. Serum 1,3-beta-D glucan assay was utilized to dictate the duration of posaconazole therapy. The patient successfully completed 9 months of oral posaconazole therapy and has not had clinical recurrence for 9 months off antifungal therapy.

Indexed as

AdultAntifungal AgentsAspergillosisAspergillus fumigatusBaltimorebeta-GlucansHumansMaleOsteomyelitisTreatment OutcomeTriazolesAntifungal Agentsbeta-GlucansposaconazoleTriazoles1,3-beta-D-glucanAspergillus fumigatusOsteomyelitisPosaconazoleVoriconazole adverse drug reaction

Identifiers

PMID32720130
OpenAlexW3043858555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.