Evidence map›Paper›PMID 32720094›Full record

ArticleHeart and vessels2021

Worsening renal function during hospitalization in elderly patients with heart failure: an independent factor of activities of daily living decline.

Ikko Kubo, Kazuhiro P Izawa, Nozomu Kajisa, Masanobu Ryu, Hideki Akasaka, Asami Ogura, Masashi Kanai, Hiroki Matsuzoe, Daisuke Matsumoto

Abstract read
PubMed Publisher
In one paragraph

Article in Heart and vessels, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ikko KuboDepartment of Rehabilitation, Yodogawa Christian Hospital, Osaka, Japan.
Kazuhiro P IzawaDepartment of Public Health, Kobe University Graduate School of Health Sciences, 10-2 Tomogaoka 7-chome, Suma, Kobe, 654-0142, Japan. izawapk@harbor.kobe-u.ac.jp.ORCID http://orcid.org/0000-0001-7262-8903
Nozomu KajisaDepartment of Rehabilitation, Yodogawa Christian Hospital, Osaka, Japan.
Masanobu RyuDepartment of Rehabilitation, Yodogawa Christian Hospital, Osaka, Japan.
Hideki AkasakaDepartment of Rehabilitation, Yodogawa Christian Hospital, Osaka, Japan.
Asami OguraDepartment of Public Health, Kobe University Graduate School of Health Sciences, 10-2 Tomogaoka 7-chome, Suma, Kobe, 654-0142, Japan.
Masashi KanaiDepartment of Public Health, Kobe University Graduate School of Health Sciences, 10-2 Tomogaoka 7-chome, Suma, Kobe, 654-0142, Japan.
Hiroki MatsuzoeDepartment of Cardiovascular Medicine, Yodogawa Christian Hospital, Osaka, Japan.
Daisuke MatsumotoDepartment of Cardiovascular Medicine, Yodogawa Christian Hospital, Osaka, Japan.
Yodogawa Christian Hospital · JPKobe University · JP

Funding

JSPS KAKENHI JP17K01500
6 · The paper itself

Abstract

This study aimed to clarify the effects of worsening renal function (WRF) during hospitalization on activities of daily living (ADL) at discharge of elderly heart failure (HF) patients. We included 323 consecutive patients hospitalized for HF who were prescribed phase I cardiac rehabilitation (CR) from November 2017 to April 2019. WRF was defined as a relative increase from baseline in serum creatinine of 25% or that in serum creatinine ≥ 0.3 mg/dL during hospitalization. The indices of ADL and physical function were the functional independence measure (FIM), short physical performance battery (SPPB) and 10-m comfortable gait speed as assessed at discharge. We compared background factors, clinical parameters, walking level before hospitalization, physical function, and FIM in two groups. Multiple regression analysis was performed with FIM at discharge as the dependent variable and items with P < 0.05 in bivariate correlation as independent variables. Ultimately, 160 patients were included and divided into the WRF group (n = 72) and non-WRF group (n = 88). FIM, SPPB, and 10-m comfortable walking speed were significantly lower in the WRF group. Moreover, even after adjustment for confounding factors (age, Hb, eGFR, CKD, GNRI, start day of standing), eGFR on admission (β = 0.12), WRF (β =  - 6.42) and walking level before hospitalization (β = - 10.00) were independent factors of ADL decline at discharge (adjusted R

Indexed as

Activities of Daily LivingHospitalizationAged, 80 and overBiomarkersCreatinineDisease ProgressionFemaleFollow-Up StudiesGlomerular Filtration RateHeart FailureHumansMalePrognosisRenal InsufficiencyRetrospective StudiesRisk FactorsBiomarkersCreatinineActivities of daily livingCardiac rehabilitation progressHeart failureMitochondrial dysfunctionOxidative stressWorsening renal function

Identifiers

PMID32720094
OpenAlexW3045838451

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.