Evidence map›Paper›PMID 32720071›Full record

ReviewCurrent oncology reports2020

Surgical Approach to Lymphedema Reduction.

Kristalyn K Gallagher, Marcos Lopez, Kathleen Iles, Meredith Kugar

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05441943 (Lymphaticovenous Anastomosis as a Surgical Treatment for Breast Cancer-Related Lymphedema), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05441943 naactive not recruitingnot on this mapstarted 2022, after this paper: background citation

Lymphaticovenous Anastomosis as a Surgical Treatment for Breast Cancer-Related Lymphedema

TypeinterventionalSponsorOdense University HospitalRan2022 to 2026Enrolled10ConditionsBreast Cancer Lymphedema, Secondary Lymphedema, Iatrogenic Lymphedema, LymphedemaArmsLymphovenous anastomosis
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Effective Treatment Approaches for Breast Cancer-Related Lymphedema.Journal of plastic and reconstructive surgery · 2026
    Article
  2. Article
  3. Mechanisms and treatments of lymphedema.Frontiers in immunology · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Lymphoscintigraphy is frequently recommended but seldom used in a "real world setting".Journal of vascular surgery. Venous and lymphatic disorders · 2024
    Article
  10. Utilizing Laparoscopic Camera with Indocyanine Green Fluorescence Filters in Lymphovenous Bypass Surgery.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2024
    Article
  11. Molecular pathophysiology of secondary lymphedema.Frontiers in cell and developmental biology · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Healthcare Practitioners' Knowledge of Lymphedema.International journal of vascular medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kristalyn K GallagherThe University of North Carolina at Chapel Hill, Campus Box 7213, 1150 POB, 170, Dr. Chapel Hill, Manning, NC, 27599-7213, USA. Kristalyn_gallagher@med.unc.edu.ORCID 0000-0002-6036-6763
Marcos LopezThe University of North Carolina at Chapel Hill, Campus Box 7213, 1150 POB, 170, Dr. Chapel Hill, Manning, NC, 27599-7213, USA.
Kathleen IlesThe University of North Carolina at Chapel Hill, Campus Box 7213, 1150 POB, 170, Dr. Chapel Hill, Manning, NC, 27599-7213, USA.
Meredith KugarThe University of North Carolina at Chapel Hill, Campus Box 7213, 1150 POB, 170, Dr. Chapel Hill, Manning, NC, 27599-7213, USA.
University of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewFor patients who have or may develop lymphedema due to oncologic resection, surgical options are available to prevent and treat this chronic disease. Here, we review the current pathophysiology, classification systems, surgical preventive techniques, and treatment options for lymphedema reduction. RECENT

findingsPreventive surgical techniques, including de-escalation of axillary surgery, sentinel lymph node biopsy (SLNB), axillary reverse mapping (ARM), and lymphedema microsurgical preventive healing approach (LYMPHA), have been shown to reduce the incidence of lymphedema. Water displacement remains the gold standard for measuring limb volume and classification of lymphedema; however, lymphoscintigraphy and ICG lymphography are two novel imaging techniques that are now utilized to characterize lymphedema and guide management. Complete decongestive therapy (CDT) remains the mainstay of treatment. Vascularized lymph node transfer (VLNT) and lymphovenous bypass have shown promising results, particularly in advanced lymphedema stages. Combination therapy, incorporating both surgical and non-surgical approaches to lymphedema, yields best patient outcomes. Lymphedema is a chronic disease wherein management requires a combination of surgical and conservative treatments. Standardization in lymphedema staging, key outcome indicators, and quantitative data will be critical to establish the absolute best practices in lymphedema diagnosis and treatment.

Indexed as

HumansLymphatic SystemLymphedemaNeoplasmsAxillary lymph node dissectionAxillary reverse mappingBreast cancerCombination therapyLymphatic microsurgical preventive healing approach (LYMPHA)Lymphaticovenous anastomosis (LVA)LymphedemaSentinel lymph node biopsySuction-assisted protein lipectomy (SAPL)Surgical excisionSurgical managementVascularized lymph node transfer (VLNT)

Identifiers

PMID32720071
OpenAlexW3045374253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.