Evidence map›Paper›PMID 32719985›Full record

ArticleEuropean journal of nutrition2021

New players in the relationship between diet and microbiota: the role of macromolecular antioxidant polyphenols.

Isabel Gutiérrez-Díaz, Nuria Salazar, Jara Pérez-Jiménez, Clara G de Los Reyes-Gavilán, Miguel Gueimonde, Sonia González

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Article in European journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Isabel Gutiérrez-DíazDepartment of Functional Biology, University of Oviedo, Oviedo, Spain.
Nuria SalazarDiet, Microbiota and Health Research Team, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.
Jara Pérez-JiménezDepartment of Metabolism and Nutrition, Institute of Food Science, Technology and Nutrition (ICTAN-CSIC), Madrid, Spain.
Clara G de Los Reyes-GavilánDiet, Microbiota and Health Research Team, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.
Miguel GueimondeDiet, Microbiota and Health Research Team, Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain.
Sonia GonzálezDepartment of Functional Biology, University of Oviedo, Oviedo, Spain. soniagsolares@uniovi.es.ORCID http://orcid.org/0000-0003-2602-7036
Instituto de Productos Lácteos de Asturias · ESUniversidad de Oviedo · ESInstituto de Ciencia y Tecnología de Alimentos y Nutrición · ES

Funding

Plan Estatal de I+D+I AGL2017-83653-R (AEI/FEDER, UE)Plan Estatal de I+D+I RTI2018-098288-B-I00 (MCIU/AEI/FEDER, UE)
6 · The paper itself

Abstract

purposeSolid evidence has emerged supporting the role of polyphenols and fibers as gut microbiota modulators. These studies have been limited to the data available in food composition databases, which did not include the food content of non-extractable polyphenols (NEPP). The main objective of this work is to quantify the intake of the different types of dietary polyphenols including NEPP and to evaluate their impact on the composition and activity of the intestinal microbiota.

methodsCross-sectional descriptive study conducted on a sample of 147 adults with no declared pathologies. Dietary intake has been registered by a semi-quantitative Food Frequency Questionnaire (FFQ) and transformed into extractable (EPP) and NEPP, and dietary fibers based on available databases. Major phylogenetic types of the intestinal microbiota were determined by qPCR and fecal SCFA quantification was performed by gas chromatography.

resultsNEPP account for two-thirds of the total polyphenols intake. A combined analysis by stepwise regression model including all dietary fiber and (poly)phenols has identified hydrolysable (poly)phenol (HPP) intake, as the best predictor of Bacteroides-Prevotella-Porphyromonas group and Bifidobacterium levels in feces. Also, HPPs were positively associated with butyric acid, while insoluble fiber was identified as a predictor of propionic acid in feces.

conclusionThe intake of macromolecular (poly)phenols could contribute to modulate the gut microbiota by increasing the levels of certain intestinal microorganisms with proven health benefits.

Indexed as

MicrobiotaPolyphenolsAntioxidantsCross-Sectional StudiesDietFecesPhylogenyAntioxidantsPolyphenolsDietary polyphenolsMacromolecular antioxidantsMicrobiotaNon-extratable polyphenols

Identifiers

PMID32719985
OpenAlexW3045839506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.