ArticleJournal of assisted reproduction and genetics2020
Ovarian stimulation outcomes among transgender men compared with fertile cisgender women.
Article in Journal of assisted reproduction and genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 55 citations in OpenAlex.
- The effect of gender-affirming testosterone therapy on ovarian function and oocyte quality in transgender men: a literature review.Journal of assisted reproduction and genetics · 2026Review
- Article
- Oocyte cryopreservation for fertility preservation in transgender and gender diverse individuals: a SWOT analysis.Journal of assisted reproduction and genetics · 2025Review
- Fertility treatments in transgender individuals: trends, clinical outcomes, and impact of testosterone on ovarian stimulation.Journal of assisted reproduction and genetics · 2025Observational
- Gender-Affirming Hysterectomy and Oophorectomy Counseling Practices for Transmasculine Adolescents.Transgender health · 2025Article
- Short and long duration testosterone treatments induce reversable subfertility in female mice using a gestational model of gender-affirming hormone therapy.Human reproduction (Oxford, England) · 2025Article
- REPRODUCTIVE HEALTH IN TRANS AND GENDER-DIVERSE PATIENTS: Gonadal tissue cryopreservation in transgender and gender-diverse people.Reproduction (Cambridge, England) · 2024Review
- Reproductive Health in Trans and Gender Diverse Patients: Effects of transmasculine gender-affirming hormone therapy on future reproductive capacity: clinical data, animal models, and gaps in knowledge.Reproduction (Cambridge, England) · 2024Review
- Androgen Inhibition of Reproductive Neuroendocrine Function in Females and Transgender Males.Endocrinology · 2024Review
- Family Building in Transgender Patients: Modern Strategies with Assisted Reproductive Technology Treatment.Transgender health · 2024Article
- Fertility treatment outcomes in transgender men with a history of testosterone therapy.F&S reports · 2023Article
- Reproductive capacity after gender-affirming testosterone therapy.Human reproduction (Oxford, England) · 2023Article
- Impaired in vitro fertilization outcomes following testosterone treatment improve with washout in a mouse model of gender-affirming hormone treatment.American journal of obstetrics and gynecology · 2023Article
- Preservation of Fertility in Transgender Men on Long-Term Testosterone Therapy: A Systematic Review of Oocyte Retrieval Outcomes During and After Exogenous Androgen Exposure.Transgender health · 2023Review
- Update on bioethical, medical and fertility issues in gender incongruence during transition age.Journal of endocrinological investigation · 2023Review
- Presence of ovarian stromal aberrations after cessation of testosterone therapy in a transgender mouse model†.Biology of reproduction · 2023Article
- Fertility, Contraception, and Fertility Preservation in Trans Individuals.Deutsches Arzteblatt international · 2023Review
- Management of testosterone around ovarian stimulation in transmasculine patients: challenging common practices to meet patient needs-2 case reports.Human reproduction (Oxford, England) · 2023Article
- Timing of testosterone discontinuation and assisted reproductive technology outcomes in transgender patients: a cohort study.F&S reports · 2023Article
- Fertility counseling guide for transgender and gender diverse people.International journal of transgender health · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare assisted reproductive technology (ART) outcomes among transgender men with those of fertile cisgender women.
methodsThis retrospective cohort study included 12 transgender men, six with no testosterone exposure and six after testosterone treatment, and 12 cisgender women (oocyte donors) who underwent ART in our institution between June 2017 and December 2019. Statistical analyses compared ART data and outcomes between three groups: cisgender women, transgender men without testosterone exposure, and transgender men after testosterone exposure. Comparisons were also made between transgender men with and without testosterone exposure.
resultsThe transgender men with no testosterone exposure (23.3 ± 4 years) were significantly younger than the transgender men who had undergone testosterone treatment (30.3 ± 3.8 years; P = 0.012) and the cisgender women (29.1 ± 3.1 years; P = 0.004). The amount of FSH used for ovulation induction (1999 ± 683 mIU/mL) was significantly lower among transgender men without prior testosterone exposure compared with that among cisgender women (3150 ± 487 mIU/mL; P = 0.007). There were no differences in the peak estradiol levels, the number of oocytes retrieved, the number of MII oocytes, and the oocyte maturity rates between the three groups. Five out of six testosterone-treated transgender men underwent embryo cryopreservation, and they all achieved good-quality embryos.
conclusionsTransgender men have an excellent response to ovulation stimulation even after long-term exposure to testosterone. Oocyte/embryo cryopreservation is, therefore, a feasible and effective way for them to preserve their fertility for future biological parenting.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.