ReviewEuropean journal of nuclear medicine and molecular imaging2021
Hybrid PET/MRI in non-small cell lung cancer (NSCLC) and lung nodules-a literature review.
Review in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Recent advances in PET/MR imaging for head and neck tumors: a systematic review of the last three years.La Radiologia medica · 2025Pooled it
- Diagnostic performance of whole-body [European radiology · 2024Pooled it
- Diagnostic potential of [Japanese journal of radiology · 2024Pooled it
- [Frontiers in medicine · 2024Pooled it
- Diagnostic impact of 18F-FDG PET/MRI over PET/CT in histiocytoses: a prospective comparative study.European journal of nuclear medicine and molecular imaging · 2026Article
- Differentiating sub-centimeter lung metastases in colorectal cancer by deep learning: a multicenter retrospective study.BMC medical imaging · 2026Article
- Impact of Deep-Learning-Based Respiratory Motion Correction on [Biomedicines · 2026Article
- Evaluation of PD-L1 Expression in Patients With Non-Small Cell Lung Cancer Using DCE-MRI Quantitative Analysis.The clinical respiratory journal · 2025Article
- Polymeric Nanoparticles for Targeted Lung Cancer Treatment: Review and Perspectives.Pharmaceutics · 2025Review
- Application of Fractal Radiomics and Machine Learning for Differentiation of Non-Small Cell Lung Cancer Subtypes on PET/MR Images.Journal of clinical medicine · 2025Article
- Delta/pre-radiomics based on enhanced CT predicts complete response in locally advanced esophageal squamous cell carcinoma.American journal of translational research · 2025Article
- CT radiomics-based model for predicting TMB and immunotherapy response in non-small cell lung cancer.BMC medical imaging · 2024Article
- [European journal of nuclear medicine and molecular imaging · 2023Article
- Current status and prospect of PET-related imaging radiomics in lung cancer.Frontiers in oncology · 2023Review
- Consistency and prognostic value of preoperative staging and postoperative pathological staging usingAnnals of nuclear medicine · 2022Article
- State of the Art: Lung Cancer Staging Using Updated Imaging Modalities.Bioengineering (Basel, Switzerland) · 2022Review
- Auxiliary Diagnosis of Lung Cancer with Magnetic Resonance Imaging Data under Deep Learning.Computational and mathematical methods in medicine · 2022Article
- PET/MRI Improves Management of Children with Cancer.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021Review
- Diagnostic efficiency of whole-bodyCancer imaging : the official publication of the International Cancer Imaging Society · 2021Article
- Magnetic Resonance Imaging Segmentation on the Basis of Boundary Tracking Algorithm in Lung Cancer Surgery.Contrast media & molecular imaging · 2021Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of hybrid PET/MRI for clinical staging is growing in several cancer forms and, consequently, PET/MRI has also gained interest in the assessment of non-small cell lung cancer (NSCLC) and lung lesions. However, lung evaluation with PET/MRI is associated with challenges related to technical issues and diagnostic image quality. We, therefore, investigated the published literature on PET/MRI for clinical staging in NSCLC or lung nodule detection specifically addressing diagnostic accuracy and technical issues.
methodsThe data originates from a systematic search performed in PubMed/MEDLINE, Embase, and Cochrane Library on hybrid PET/MRI in patients with cancer for a scoping review published earlier ( https://doi.org/10.1007/s00259-019-04402-8 ). Studies in English and German evaluating the diagnostic performance of hybrid PET/MRI for NSCLC or lung nodule detection in cancer patients were selected. Data reported in peer-reviewed journals without restrictions to year of publication were included.
resultsA total of 3138 publications were identified from which 116 published 2012-2018 were included. Of these, nine studies addressed PET/MRI in NSCLC (4) or lung nodule detection (5). Overall, PET/MRI did not provide advantages in preoperative T- and N-staging in NSCLC compared to PET/CT. The data on M-staging were too few for conclusions to be drawn. The lung nodule detection rate of PET/MRI was comparable to that of PET/CT for FDG-avid nodules larger than 10 mm, but the sensitivity of PET/MRI for detection of non-FDG-avid nodules smaller than 5 mm was low.
conclusionPET/MRI did not provide advantages in T- and N-staging of NSCLC compared to PET/CT. PET/MRI had a comparable sensitivity for detection of FDG-avid lung nodules and nodules over 10 mm, but PET/CT yielded a higher detection rate in non FDG-avid lung nodules under 5 mm. With PET/MRI, the overall detection rate for lung nodules in various cancer types remains inferior to that of PET/CT due to the lower diagnostic performance of MRI than CT in the lungs.
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