ArticleFrontiers in veterinary science2020
Vaginal Microbiota Changes During Estrous Cycle in Dairy Heifers.
Article in Frontiers in veterinary science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 87 citations in OpenAlex.
- Characterization of the vaginal bacterial microbiota of sheep exhibiting abortion or repeat breeder syndrome.Veterinary and animal science · 2026Article
- Postpartum Uterine Diseases in Dairy Cattle: Integrating Microbiology, Immunology, and Reproductive Physiology.Microorganisms · 2026Review
- Metagenomic analysis of the vaginal microbiota in cows with ovarian cysts.Journal of veterinary research · 2026Article
- Addition of lactic acid bacteria to diluted ram semen as vehicle for vaginal inoculation: interaction with seminal microbiota, sperm quality and antibacterial in vitro effect against Mycoplasma agalactiae.BMC veterinary research · 2026Article
- Vaginal Microbiota Composition and Its Relationship with Fertility in Repeat Breeder Dairy Cows.Biology · 2026Article
- Characterization of the Endometrial Microbiota of Healthy Mares Across the Estrous Cycle.Animals : an open access journal from MDPI · 2026Article
- Effects of feeding a Bacillus-based probiotic on nutrient utilization and microbiota profile in the rumen and reproductive tract of beef heifers receiving a forage-based diet.Journal of animal science · 2026Article
- Article
- A metagenomic analysis of the gut microbiota in a mouse model of fish allergy.Frontiers in microbiology · 2026Article
- The influence of vaginal microbiota on ewe fertility: a metagenomic and functional genomic approach.Microbiome · 2025Article
- Identification of Naturally Occurring Inhabitants of Vaginal Microbiota in Cows and Determination of Their Antibiotic Sensitivity.Veterinary sciences · 2025Article
- Vaginal microbiota and circulating interferon-stimulated genes in lactating dairy cows at and following time of artificial insemination.Journal of animal science · 2025Article
- Fundamentals of microbiome-based therapies for reproductive tract inflammatory diseases in domestic animals.Animal reproduction · 2025Review
- Article
- Combined analysis of 16S rRNA gene sequencing data reveals core vaginal bacteria across livestock species.Frontiers in microbiology · 2025Article
- Microbial Gatekeepers of Fertility in the Female Reproductive Microbiome of Cattle.International journal of molecular sciences · 2024Review
- Characterization of bovine vaginal microbiota using 16S rRNA sequencing: associations with host fertility, longevity, health, and production.Scientific reports · 2024Article
- Reproductive Tract Microbiota of Mares.Veterinary sciences · 2024Review
- Updates and Current Challenges in Reproductive Microbiome: A Comparative Analysis between Cows and Women.Animals : an open access journal from MDPI · 2024Review
- Uterine Disease in Dairy Cows: A Comprehensive Review Highlighting New Research Areas.Veterinary sciences · 2024Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The vaginal microbiota plays an important role in the health of dairy cattle, and it could be manipulated for the prevention and treatment of reproduction-related infections. The present study profiles and compares the vaginal microbiota of healthy dairy heifers during the estrous cycle focusing the results in follicular (estrus) and luteal (diestrus) phases using 16S rRNA sequencing of the V3-V4 hypervariable region. Twenty 13-16-months-old virgin dairy heifers from a single farm were included in this study. Vaginal swabs and blood samples were obtained during estrus (6-8 h before artificial insemination) and diestrus (14 days after insemination). Estrus was evaluated by an activity monitoring system and confirmed with plasma progesterone immunoassay. Results showed that the taxonomic composition of the vaginal microbiota was different during the follicular and luteal phases. At the phylum level, the most abundant bacterial phyla were Tenericutes, Firmicutes, and Bacteroidetes which comprised more than 75% of the vaginal microbiota composition. The next more abundant phyla, in order of decreasing abundance, were Proteobacteria, Actinobacteria, Fusobacteria, Epsilonbacteraeota, and Patescibacteria. Together with Tenericutes, Firmicutes, and Bacteroidetes represented more than 96% of the bacterial composition.
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