Evidence map›Paper›PMID 32719735›Full record

ArticleInternational Solid-State Sensors, Actuators and Microsystems Conference : [proceedings]. International Conference on Solid-State Sensors, Actuators, and Microsystems2019

NON-ENZYMATIC ELECTROCHEMICAL DETECTION OF GLUTAMATE USING TEMPLATED POLYMER-BASED TARGET RECEPTORS.

Habib M N Ahmad, Bo Si, Gaurab Dutta, John R Csoros, William Rudolf Seitz, Edward Song

Abstract read
In one paragraph

Article in International Solid-State Sensors, Actuators and Microsystems Conference : [proceedings]. International Conference on Solid-State Sensors, Actuators, and Microsystems, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Habib M N AhmadDepartment of Electrical and Computer Engineering, University of New Hampshire, USA.
Bo SiDepartment of Electrical and Computer Engineering, University of New Hampshire, USA.
Gaurab DuttaDepartment of Electrical and Computer Engineering, University of New Hampshire, USA.
John R CsorosDepartment of Chemistry, University of New Hampshire, USA.
William Rudolf SeitzDepartment of Chemistry, University of New Hampshire, USA.
Edward SongDepartment of Electrical and Computer Engineering, University of New Hampshire, USA.

Funding

TLR-TRIF mediated induction of GLI3 modulates innate inflammatory responsesP20GM113131 · NIGMS · UNIVERSITY OF NEW HAMPSHIRE · PI W Kelley THOMAS · 2017 to 2026
$22.8M
NIGMS NIH HHS P20 GM113131
6 · The paper itself

Abstract

We present a novel electrochemical biosensing platform for the detection of neurotransmitter glutamate using templated polymer-based target receptors. Our sensing approach demonstrates, for the first time, a non-enzymatic approach without the need of glutamate oxidase, leading to a more specific and rapid response. The proposed detection principle is based on the following two claims: (1) our templated polymer-based receptor results in specific molecular recognition of the target glutamate and, (2) upon target binding, the polymer undergoes a conformation change which can then be measured via electrochemical techniques. This sensing platform has the potential to provide direct monitoring of a variety of non-electroactive species and to eliminate the incorporation of enzymes thereby providing a simpler and more robust alternative to enzyme-based sensors.

Indexed as

BiosensingElectrochemical DetectionGlutamateNeurotransmitterNon-enzymaticTemplated Polymer

Identifiers

PMID32719735
PMCPMC7384742

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.