ArticleNature chemical biology2020
Enzymatic C-H activation of aromatic compounds through CO
Article in Nature chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Enzymatic Cascades for Stereoselective and Regioselective Amide Bond Assembly.Angewandte Chemie (International ed. in English) · 2025Article
- Expanding the repertoire of imine reductases by mining divergent biosynthetic pathways for promiscuous reactivity.Chem catalysis · 2024Article
- Light-driven C-H activation mediated by 2D transition metal dichalcogenides.Nature communications · 2024Article
- Light-driven C-H activation mediated by 2D transition metal dichalcogenides.Research square · 2024Article
- Machine Learning and Quantum Calculation for Predicting Yield in Cu-Catalyzed P-H Reactions.Molecules (Basel, Switzerland) · 2023Article
- Enzymatic Conversion of COChemical reviews · 2023Review
- EnzymaticACS sustainable chemistry & engineering · 2022Article
- Immobilization of carbonic anhydrase for COApplied microbiology and biotechnology · 2022Review
- Toolbox for the structure-guided evolution of ferulic acid decarboxylase (FDC).Scientific reports · 2022Article
- Directed evolution of prenylated FMN-dependent Fdc supports efficient in vivo isobutene production.Nature communications · 2021Article
- Synthetic Enzyme-Catalyzed COChemSusChem · 2021Review
- Structure and Mechanism ofACS catalysis · 2021Article
- Biocatalytic C-C Bond Formation for One Carbon Resource Utilization.International journal of molecular sciences · 2021Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
The direct C-H carboxylation of aromatic compounds is an attractive route to the corresponding carboxylic acids, but remains challenging under mild conditions. It has been proposed that the first step in anaerobic microbial degradation of recalcitrant aromatic compounds is a UbiD-mediated carboxylation. In this study, we use the UbiD enzyme ferulic acid decarboxylase (Fdc) in combination with a carboxylic acid reductase to create aromatic degradation-inspired cascade reactions, leading to efficient functionalization of styrene through CO
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.