ArticleHypertension research : official journal of the Japanese Society of Hypertension2021
Concurrent analogous organ damage in the brain, eyes, and kidneys in malignant hypertension: reversible encephalopathy, serous retinal detachment, and proteinuria.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 31 citations in OpenAlex.
- Contrastive Machine Learning to Quantify Hypertensive Multiorgan Damage and Identify New Disease Phenotypes: A Multinational Multimodal Study.Circulation · 2026Article
- A novel idiopathic transient tubulopathy associated with exercise-induced-seizures: A case report.Epilepsy & behavior reports · 2026Article
- Hypertensive Emergency Presenting With Isolated Cranial Nerve III Palsy and Subsequent Intracranial Hemorrhage.Cureus · 2025Article
- Article
- Construction and validation of a multimodal predictive model incorporating catecholamines and uric acid for early detection of hypertensive organ damage.Frontiers in endocrinology · 2025Article
- Role of aldosterone in various target organ damage in patients with hypertensive emergency: a cross-sectional study.BMC nephrology · 2024Article
- The Increasing Problem of Resistant Hypertension: We'll Manage till Help Comes!Medical sciences (Basel, Switzerland) · 2024Review
- Malignant hypertension: current challenges, prevention strategies, and future perspectives.Frontiers in cardiovascular medicine · 2024Review
- Genetic, clinical, and pathological study of patients with severe hypertension-associated renal microangiopathy.Journal of nephrology · 2023Article
- Impact of early initiation of renin-angiotensin blockade on renal function and clinical outcomes in patients with hypertensive emergency: a retrospective cohort study.BMC nephrology · 2023Article
- Cardiac Complications of Hypertensive Emergency: Classification, Diagnosis and Management Challenges.Journal of cardiovascular development and disease · 2022Review
- Hypertensive eye disease.Nature reviews. Disease primers · 2022Review
- Article
- Potential common pathophysiological pathway of hypertension-mediated organ damage in hypertensive emergency.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Malignant hypertension and multiorgan damage: mechanisms to be elucidated and countermeasures.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
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Authors and funding
14 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Malignant hypertension, a form of hypertensive emergency, causes acute damage in vital organs such as the brain, eyes, and kidneys. We aimed to examine the concurrency of acute hypertensive damage across the target organs to elucidate the underlying analogous pathophysiology. This single-center retrospective study evaluated the characteristics of organ damage, short-term clinical course, and interorgan relationships in patients with malignant hypertension treated between 2008 and 2019. Baseline characteristics of 20 patients who met our inclusion criteria were mean age 48 ± 13 years and blood pressure 222 ± 18/142 ± 16 mmHg; the median estimated glomerular filtration rate and urinary protein level were 49 mL/min/1.73 m
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