Trial reportScientific reports2020
Neuroplastic effects of end-effector robotic gait training for hemiparetic stroke: a randomised controlled trial.
Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04054739 (Effects of Robotic Gait Training on Cortical Activity and Gait Function in Hemiparetic Stroke), which is not on this map. Cited by 34 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Robotic Gait Training on Cortical Activity and Gait Function in Hemiparetic Stroke
Who cites it
34 citing papers in PubMed, 6 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Post-stroke lower limb rehabilitation: a comparative study between exoskeleton robots and traditional gait training.Journal of neuroengineering and rehabilitation · 2026Pooled it
- [Gait Training Using Robotic Devices in Subjects With Stroke: An Overview of Systematic Reviews and Meta-analysis].Revista de neurologia · 2026Pooled it
- Robotic Training and Neural Reorganization in Stroke: A Systematic Review.F1000Research · 2026Pooled it
- Electromechanical-assisted training for walking after stroke.The Cochrane database of systematic reviews · 2025Pooled it
- Clinical indications and protocol considerations for selecting initial body weight support levels in gait rehabilitation: a systematic review.Journal of neuroengineering and rehabilitation · 2024Pooled it
- Effects of soft robotic exosuit on ambulation ability in stroke patients: a systematic review.Biomedical engineering online · 2023Pooled it
- Development and Upgrade of a Robot That Enables Three-Dimensional Trunk Motion and Lower Limb Exercise for Stroke Patients: A Pilot Clinical Investigation Including a User Feasibility Test.BioMed research international · 2026Trial
- Neural mechanisms underlying the improvement of gait disturbances in stroke patients through robot-assisted gait training based on QEEG and fNIRS: a randomized controlled study.Journal of neuroengineering and rehabilitation · 2025Trial
- Effects of exoskeleton rehabilitation robot training on neuroplasticity and lower limb motor function in patients with stroke.BMC neurology · 2025Trial
- Robot-assisted gait training improves walking and cerebral connectivity in children with unilateral cerebral palsy.Pediatric research · 2024Trial
- Abnormal synergistic gait mitigation in acute stroke using an innovative ankle-knee-hip interlimb humanoid robot: a preliminary randomized controlled trial.Scientific reports · 2021Trial
- Post-Stroke Rehabilitation: Neurophysiology Processes of Bilateral Movement Training and Interlimb Coupling-A Systematic Review.Journal of clinical medicine · 2025Review
- May Patients with Chronic Stroke Benefit from Robotic Gait Training with an End-Effector? A Case-Control Study.Journal of functional morphology and kinesiology · 2025Article
- Re-Evaluating the Role of Robotic Gait Training in Post-Stroke Balance Rehabilitation.Brain sciences · 2025Article
- Effect and optimal exercise prescription of robot-assisted gait training on lower extremity motor function in stroke patients: a network meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Review
- The effects of different types of RAGT on balance function in stroke patients with low levels of independent walking in a convalescent rehabilitation hospital.Open medicine (Warsaw, Poland) · 2025Article
- Case Report: Robot-assisted gait training with the wearable cyborg hybrid assistive limb 2S size in three children with cerebral palsy.Frontiers in rehabilitation sciences · 2025Article
- Changes in body composition, physical fitness and quality of life on robotic gait assisted training in patients with Guillain-Barré Syndrome: a case report.Physical activity and nutrition · 2024Article
- Review
- Applications of Functional Near-Infrared Spectroscopy (fNIRS) Neuroimaging During Rehabilitation Following Stroke: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Detecting neuroplastic changes during locomotor neurorehabilitation is crucial for independent primal motor behaviours. However, long-term locomotor training-related neuroplasticity remains unexplored. We compared the effects of end-effector robot-assisted gait training (E-RAGT) and bodyweight-supported treadmill training (BWST) on cortical activation in individuals with hemiparetic stroke. Twenty-three men and five women aged 53.2 ± 11.2 years were recruited and randomly assigned to participate in E-RAGT (n = 14) or BWST (n = 14) for 30 min/day, 5 days/week, for 4 weeks. Cortical activity, lower limb motor function, and gait speed were evaluated before and after training. Activation of the primary sensorimotor cortex, supplementary motor area, and premotor cortex in the affected hemisphere significantly increased only in the E-RAGT group, although there were no significant between-group differences. Clinical outcomes, including the Fugl-Meyer assessment (FMA), timed up and go test, and 10-m walk test scores, improved after training in both groups, with significantly better FMA scores in the E-RAGT group than in the BWST group. These findings suggest that E-RAGT effectively improves neuroplastic outcomes in hemiparetic stroke, although its superiority over conventional training remains unclear. This may have clinical implications and provides insight for clinicians interested in locomotor neurorehabilitation after hemiparetic stroke.Trial Registration: ClinicalTrials.gov Identifier NCT04054739 (12/08/2019).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.