Evidence map›Paper›PMID 32719159›Full record

ArticleInfection and immunity2020

Importance of the Immunodominant CD8

Matthew P Gibbins, Katja Müller, Maya Glover, Jasmine Liu, Elyzana D Putrianti, Karolis Bauza, Arturo Reyes-Sandoval, Kai Matuschewski, Olivier Silvie, Julius Clemence R Hafalla

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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  6. Frontiers in cell and developmental biology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Matthew P GibbinsDepartment of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.ORCID 0000-0002-7166-044X
Katja MüllerParasitology Unit, Max Planck Institute for Infection Biology, Berlin, Germany.
Maya GloverDepartment of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Jasmine LiuDepartment of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Elyzana D PutriantiParasitology Unit, Max Planck Institute for Infection Biology, Berlin, Germany.
Karolis BauzaJenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Arturo Reyes-SandovalJenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-2648-1696
Kai MatuschewskiParasitology Unit, Max Planck Institute for Infection Biology, Berlin, Germany.
Olivier SilvieSorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, CIMI-Paris, Paris, France.
Julius Clemence R HafallaDepartment of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom Julius.Hafalla@lshtm.ac.uk.ORCID 0000-0002-5452-9263
London School of Hygiene & Tropical Medicine · GBHumboldt-Universität zu Berlin · DEUniversity of Oxford · GBCal Poly Humboldt · USCentre National de la Recherche Scientifique · FR

Funding

National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/L000601/1Wellcome TrustWellcome Trust 097395/Z/11/Z
6 · The paper itself

Abstract

The circumsporozoite protein (CSP) builds up the surface coat of sporozoites and is the leading malaria pre-erythrocytic-stage vaccine candidate. CSP has been shown to induce robust CD8

Indexed as

AnimalsAntibodies, ProtozoanAntigen PresentationAntigens, ProtozoanCD8-Positive T-LymphocytesDisease Models, AnimalEpitopes, T-LymphocyteImmunizationMalariaMalaria VaccinesMiceMice, Inbred BALB CMice, Inbred C57BLPeptide FragmentsPlasmodium bergheiProtozoan ProteinsAntibodies, ProtozoanAntigens, Protozoancircumsporozoite protein, ProtozoanEpitopes, T-LymphocyteMalaria VaccinesPeptide FragmentsProtozoan Proteinsapicomplexan parasitesCD8+ T cellscircumsporozoitemalariamurine modelsparasitePlasmodiumprotectionvaccine

Identifiers

PMID32719159
PMCPMC7504970
OpenAlexW3046029114

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.