Evidence map›Paper›PMID 32719101›Full record

ArticleeNeuro

Electric Field Application

Elana Sefton, Stephanie N Iwasa, Taylor Morrison, Hani E Naguib, Milos R Popovic, Cindi M Morshead

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Bioreactor Technologies for Enhanced Organoid Culture.International journal of molecular sciences · 2023
    Review
  8. Guest Editorial Special Section on Functional Recovery and Brain Plasticity.IEEE open journal of engineering in medicine and biology · 2023
    Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Elana SeftonInstitute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada, M5S 3G9.
Stephanie N IwasaThe KITE Research Institute, Toronto Rehabilitation Institute - University Health Network, Toronto, Ontario, Canada, M5G 2A2.
Taylor MorrisonDepartment of Mechanical & Industrial Engineering, University of Toronto, Toronto, Ontario, Canada, M5S 3G8.
Hani E NaguibInstitute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada, M5S 3G9.
Milos R PopovicInstitute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada, M5S 3G9.
Cindi M MorsheadInstitute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada, M5S 3G9 cindi.morshead@utoronto.ca.
University of Toronto · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep brain stimulation (DBS), which uses electrical stimulation, is a well-established neurosurgical technique used to treat neurologic disorders. Despite its broad therapeutic use, the effects of electrical stimulation on brain cells is not fully understood. Here, we examine the effects of electrical stimulation on neural stem and progenitor cells (collectively neural precursor cells; NPCs) from the subventricular zone in the adult forebrain of C57BL/6J mice. Previous work has demonstrated that adult-derived NPCs are electro sensitive and undergo rapid and directed migration in response to application of clinically relevant electric fields (EFs). We examine NPC proliferation kinetics and their differentiation profile following EF application using

Indexed as

Neural Stem CellsAnimalsCell DifferentiationCell MovementCell ProliferationMiceMice, Inbred C57BLNeurogenesisNeuronsProsencephaloncell survivalEGFRelectrical stimulationneural stem cellsquiescencesFRP2

Identifiers

PMID32719101
PMCPMC7452733
OpenAlexW3046081298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.