Evidence map›Paper›PMID 32719093›Full record

ArticleAJNR. American journal of neuroradiology2020

Characterizing the Subcortical Structures in Youth with Congenital Heart Disease.

K Fontes, F Courtin, C V Rohlicek, C Saint-Martin, G Gilbert, K Easson, A Majnemer, A Marelli, M M Chakravarty, M Brossard-Racine

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In one paragraph

Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

K FontesFrom the Advances in Brain and Child Health Development Research Laboratory (K.F., F.C., K.E., M.B.-R.), Centre for Outcomes Research & Evaluation, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.ORCID 0000-0002-2093-448X
F CourtinFrom the Advances in Brain and Child Health Development Research Laboratory (K.F., F.C., K.E., M.B.-R.), Centre for Outcomes Research & Evaluation, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.ORCID 0000-0001-6640-8859
C V RohlicekDepartment of Pediatrics, Division of Cardiology (C.V.R.).ORCID 0000-0002-6425-1138
C Saint-MartinDepartment of Medical Imaging, Division of Pediatric Radiology (C.S.-M.).ORCID 0000-0002-3632-7502
G GilbertDepartment of Pediatrics, Division of Neurology (A. Majnemer).ORCID 0000-0002-9960-1062
K EassonFrom the Advances in Brain and Child Health Development Research Laboratory (K.F., F.C., K.E., M.B.-R.), Centre for Outcomes Research & Evaluation, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.ORCID 0000-0002-5650-3673
A Majnemerand Department of Pediatrics, Division of Neonatology (M.B.-R.), Montreal Children's Hospital McGill University Health Centre, Montreal, Quebec, Canada.ORCID 0000-0001-7712-3509
A MarelliSchool of Physical and Occupational Therapy (A. Majnemer, M.B.-R.).ORCID 0000-0002-1784-8206
M M ChakravartyDepartments of Psychiatry (M.M.C.).ORCID 0000-0002-0759-5508
M Brossard-RacineFrom the Advances in Brain and Child Health Development Research Laboratory (K.F., F.C., K.E., M.B.-R.), Centre for Outcomes Research & Evaluation, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada marie.brossardracine@mcgill.ca.ORCID 0000-0003-0641-0054

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeCongenital heart disease is a leading cause of neurocognitive impairment. Many subcortical structures are known to play a crucial role in higher-order cognitive processing. However, comprehensive anatomic characterization of these structures is currently lacking in the congenital heart disease population. Therefore, this study aimed to compare the morphometry and volume of the globus pallidus, striatum, and thalamus between youth born with congenital heart disease and healthy peers. MATERIALS AND

methodsWe recruited youth between 16 and 24 years of age born with congenital heart disease who underwent cardiopulmonary bypass surgery before 2 years of age (

resultsSmaller surface area and inward bilateral displacement across the lateral surfaces of the globus pallidus were concentrated anteriorly in the congenital heart disease group compared with controls (

conclusionsThis study reports morphometric alterations in youth with congenital heart disease in the absence of volume reductions, suggesting that volume alone is not sufficient to detect and explain subtle neuroanatomic differences in this clinical population.

Indexed as

AdolescentFemaleGlobus PallidusHeart Defects, CongenitalHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleNeuroimagingThalamusYoung Adult

Identifiers

PMID32719093
PMCPMC7658863

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.