ArticleAntimicrobial agents and chemotherapy2020
HIV Coinfection Is Associated with Low-Fitness
Open access · hybridAbstract read
In one paragraph
Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Impact of HIV and hospitalization on the incidence of subsequent rifampicin-resistant tuberculosis after initiation of first-line tuberculosis treatment: a retrospective cohort study in South Africa.EClinicalMedicine · 2025Article
- Molecular Epidemiology ofMicroorganisms · 2025Review
- Population structure and emergence of resistance to new and repurposed drugs in XDR-TB: insights from a 10-year genomic study in the Western Cape, South Africa review.Frontiers in cellular and infection microbiology · 2025Article
- Mutational Dynamics Related to Antibiotic Resistance inMicroorganisms · 2024Article
- BorderlineMicrobial genomics · 2023Article
- Isoniazid and Rifampicin Resistance-Conferring Mutations inPathogens (Basel, Switzerland) · 2023Review
- Molecular characterization of genetic mutations with fitness loss in pulmonary tuberculosis patients associated with HIV co-infection in Northwest Amhara, Ethiopia.SAGE open medicine · 2023Article
- Review
- Potential contribution of HIV during first-line tuberculosis treatment to subsequent rifampicin-monoresistant tuberculosis and acquired tuberculosis drug resistance in South Africa: a retrospective molecular epidemiology study.The Lancet. Microbe · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 12 institutions in 11 countries.
Chloé LoiseauSwiss Tropical and Public Health Institute, Basel, Switzerland.
Daniela BritesSwiss Tropical and Public Health Institute, Basel, Switzerland.
Miriam ReinhardSwiss Tropical and Public Health Institute, Basel, Switzerland.
Kathrin ZürcherInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Sonia BorrellSwiss Tropical and Public Health Institute, Basel, Switzerland.
Marie BallifInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Lukas FennerInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0003-3309-4835
Helen CoxInstitute of Infectious Disease and Molecular Medicine and Wellcome Centre for Infectious Disease Research in Africa, University of Cape Town, Cape Town, South Africa.
Liliana K RutaihwaSwiss Tropical and Public Health Institute, Basel, Switzerland.
Robert J WilkinsonWellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory, South Africa.
Marcel YotebiengDivision of General Internal Medicine, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.
E Jane CarterDepartment of Medicine, Moi University School of Medicine, and Moi Teaching and Referral Hospital, Eldoret, Kenya.
Alash'le AbimikuInstitute of Human Virology, Abuja, Nigeria.
Olivier MarcyCentre de Prise en Charge de Recherche et de Formation, Yopougon, Abidjan, Côte d'Ivoire.
Eduardo GotuzzoTB Research Unit, Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru.
Anchalee AvihingsanonThe HIV Netherlands Australia Thailand (HIV-NAT) Research Collaboration, Thai Red Cross AIDS Research Centre and Tuberculosis Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Nicola ZetolaUniversity of Pennsylvania, Philadelphia, Pennsylvania, USA.
Basra DoullaCentral Tuberculosis Reference Laboratory, Dar es Salaam, Tanzania.
Erik C BöttgerInstitute of Medical Microbiology, University of Zurich, Zurich, Switzerland.
Matthias EggerInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Sebastien GagneuxSwiss Tropical and Public Health Institute, Basel, Switzerland sebastien.gagneux@swisstph.ch.
Swiss Tropical and Public Health Institute · CHUniversity of Bern · CHUniversity of Cape Town · ZAAlbert Einstein College of Medicine · USChulalongkorn University · THIfakara Health Institute · TZInstitute of Human Virology · NGMoi University · KEUniversidad Peruana Cayetano Heredia · PEUniversité de Bordeaux · FRUniversity of Pennsylvania · USUniversity of Zurich · CH
Funding
North American AIDS Cohorts on Collaboration and Design (NAACCORD)U01AI069918 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Keri Nicole Althoff, RICHARD Douglas MOORE · 2006 to 2026
$65.2MEast Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional ConsortiumU01AI069911 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI AGGREY SEMWENDERO SEMEERE, Kara Kay Wools-Kaloustian · 2006 to 2026
$57.7MObservational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9MThe Asia-Pacific HIV Research CollaborationU01AI069907 · NIAID · FOUNDATION FOR AIDS RESEARCH · PI ANNETTE H SOHN · 2006 to 2026
$44.8MCCASAnet: Caribbean, Central and South America NetworkU01AI069923 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Pedro Enrique Cahn, Jessica L Castilho · 2006 to 2026
$41.6M"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8MWADA (West Africa Database on Antiretroviral Therapy) CollaborationU01AI069919 · NIAID · UNIVERSITY OF BORDEAUX II · PI Didier Koumavi Ekouevi, Antoine Jaquet · 2006 to 2026
$29.9MHarmonist: A Scalable Toolkit for Standardizing and Coordinating Data Sharing Across International Research NetworksR24AI124872 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Stephany Norah Duda · 2016 to 2026
$12.5MNIAID NIH HHS R24 AI124872NIAID NIH HHS U01 AI069907NIAID NIH HHS U01 AI069911NIAID NIH HHS U01 AI069918NIAID NIH HHS U01 AI069919NIAID NIH HHS U01 AI069923NIAID NIH HHS U01 AI069924NIAID NIH HHS U01 AI096299Wellcome Trust 104803Wellcome Trust 203135
Abstract
We analyzed 312 drug-resistant genomes of
Indexed as
HIV InfectionsMycobacterium tuberculosisTuberculosis, Multidrug-ResistantAntitubercular AgentsBacterial ProteinsDNA-Directed RNA PolymerasesHumansMicrobial Sensitivity TestsMutationRifampinAntitubercular AgentsBacterial ProteinsDNA-Directed RNA PolymerasesRifampindrug resistancefitness costHIV-TB coinfectionMycobacterium tuberculosisrifampicin
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.