Evidence map›Paper›PMID 32718931›Full record

ArticleBiology open2020

Effect of serotonin modulation on dystrophin-deficient zebrafish.

Janelle M Spinazzola, Matthias R Lambert, Devin E Gibbs, James R Conner, Georgia L Krikorian, Prithu Pareek, Carlo Rago, Louis M Kunkel

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. PDE10A Inhibition Reduces the Manifestation of Pathology in DMD Zebrafish and Represses the Genetic Modifier PITPNA.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Janelle M SpinazzolaDivision of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA.
Matthias R LambertDivision of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0001-8300-3124
Devin E GibbsDivision of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA.
James R ConnerDivision of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA.
Georgia L KrikorianDivision of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA.
Prithu PareekDivision of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-2722-6398
Carlo RagoDMD Therapeutics Inc., Seattle, WA, USA.
Louis M KunkelDivision of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA kunkel@enders.tch.harvard.edu.ORCID 0000-0001-6126-0242
Boston Children's Hospital · US

Funding

Mouse Neurodevelopmental Behavior CoreU54HD090255 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI POMEROY, SCOTT LOREN · 2016 to 2020
$5.2M
NICHD NIH HHS U54 HD090255
6 · The paper itself

Abstract

Duchenne muscular dystrophy (DMD) is a progressive muscle-wasting disease caused by mutation of the

Indexed as

AnimalsBirefringenceDrug Evaluation, PreclinicalDystrophinMonoamine Oxidase InhibitorsReceptors, SerotoninSelective Serotonin Reuptake InhibitorsSerotoninSerotonin Receptor AgonistsSurvival AnalysisZebrafishDystrophinMonoamine Oxidase InhibitorsReceptors, SerotoninSelective Serotonin Reuptake InhibitorsSerotoninSerotonin Receptor AgonistsDrug screeningDuchenne muscular dystrophySerotoninZebrafish

Identifiers

PMID32718931
PMCPMC7473644
OpenAlexW3045437373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.