Evidence map›Paper›PMID 32718562›Full record

ReviewGastroenterology clinics of North America2020

EndoFLIP in the Esophagus: Assessing Sphincter Function, Wall Stiffness, and Motility to Guide Treatment.

Erica N Donnan, John E Pandolfino

Registry-linked trialAbstract readReview
In one paragraph

Review in Gastroenterology clinics of North America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07458555 (Impact of Anesthetics on Esophageal Motility as Assessed by Functional Luminal Imaging Probe), which is not on this map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07458555 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Impact of Anesthetics on Esophageal Motility as Assessed by Functional Luminal Imaging Probe (FLIP) Topography

TypeinterventionalSponsorBaylor Research InstituteRan2024 to 2026Enrolled30ConditionsAchalasia, Esophageal, Esophagogastric Junction Outflow Obstruction, Spastic Esophageal DisordersArmsFLIP Imaging under various standard of care anesthetics in the context of endotracheal intubation.
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Functional Lumen Imaging Probe Panometry.Gastrointestinal endoscopy clinics of North America · 2025
    Review
  14. Review
  15. Review
  16. Article
  17. A review of recent developments in the imaging of disorders of gut-brain interaction.Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi · 2025
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Erica N DonnanDivision of Gastroenterology and Hepatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; NMH/Arkes Family Pavilion, Suite 1400, 676 North Saint Clair, Chicago, IL 60611, USA. Electronic address: erica.donnan@northwestern.edu.
John E PandolfinoDivision of Gastroenterology and Hepatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; NMH/Arkes Family Pavilion, Suite 1400, 676 North Saint Clair, Chicago, IL 60611, USA.

Funding

Role of altered response to volumetric distension in esophageal diseaseP01DK117824 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PANDOLFINO, JOHN E · 2018 to 2022
$7.3M
NIDDK NIH HHS P01 DK117824
6 · The paper itself

Abstract

The functional luminal imaging probe (FLIP) uses high-resolution planimetry to provide a three-dimensional image of the esophageal lumen by measuring diameter, volume, and pressure changes. Literature surrounding use of FLIP has demonstrated its clinical utility as a diagnostic tool and as a device to guide and measure response to therapy. FLIP can assess and guide treatments for esophageal disease states including gastroesophageal reflux disease, achalasia, and eosinophilic esophagitis. FLIP may become the initial test for patients with undifferentiated dysphagia at their index endoscopy. This article summarizes use of FLIP in assessing sphincter function, wall stiffness, and motility to guide treatments.

Indexed as

Diagnostic Techniques, Digestive SystemElasticityGastrointestinal MotilityBiomechanical PhenomenaDiagnostic ImagingEndoscopy, GastrointestinalEosinophilic EsophagitisEsophageal AchalasiaEsophageal Sphincter, LowerEsophagogastric JunctionEsophagusGastroesophageal RefluxAchalasiaDysphagiaEndoFLIPFLIPGastroesophageal refluxImpedance

Identifiers

PMID32718562
PMCPMC7387752

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.