Evidence map›Paper›PMID 32718224›Full record

ArticleThyroid : official journal of the American Thyroid Association2021

Human Type 1 Iodothyronine Deiodinase (

Monica M França, Alina German, Gustavo W Fernandes, Xiao-Hui Liao, Antonio C Bianco, Samuel Refetoff, Alexandra M Dumitrescu

Open access · greenAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Guideline
  2. Review
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  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Severe neurodevelopmental phenotype, diagnostic, and treatment challenges in patients with SECISBP2 deficiency.Genetics in medicine : official journal of the American College of Medical Genetics · 2024
    Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Are We Restoring Thyroid Hormone Signaling in Levothyroxine-Treated Patients With Residual Symptoms of Hypothyroidism?Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2023
    Review
  15. Review
  16. Thyroid Hormone Metabolism: A Historical Perspective.Thyroid : official journal of the American Thyroid Association · 2023
    Article
  17. Review
  18. The relevance of TThe lancet. Diabetes & endocrinology · 2022
    Review
  19. Primary hypothyroidism and quality of life.Nature reviews. Endocrinology · 2022
    Review
  20. NovelThyroid : official journal of the American Thyroid Association · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Monica M FrançaSection of Endocrinology Diabetes and Metabolism, Department of Medicine, The University of Chicago, Chicago, Illinois, USA.
Alina GermanDepartment of Pediatric Endocrine Unit, Bnei Zion Medical Center, Clalit Health Service and Technion-the Israel Institute of Technology, Haifa, Israel.
Gustavo W FernandesSection of Endocrinology Diabetes and Metabolism, Department of Medicine, The University of Chicago, Chicago, Illinois, USA.
Xiao-Hui LiaoSection of Endocrinology Diabetes and Metabolism, Department of Medicine, The University of Chicago, Chicago, Illinois, USA.
Antonio C BiancoSection of Endocrinology Diabetes and Metabolism, Department of Medicine, The University of Chicago, Chicago, Illinois, USA.
Samuel RefetoffSection of Endocrinology Diabetes and Metabolism, Department of Medicine, The University of Chicago, Chicago, Illinois, USA.
Alexandra M DumitrescuSection of Endocrinology Diabetes and Metabolism, Department of Medicine, The University of Chicago, Chicago, Illinois, USA.
University of Chicago · USTechnion – Israel Institute of Technology · ILUniversity of Illinois Chicago · US

Funding

THYROID PHYSIOLOGY STUDIES OF INHERITED DISORDERSR01DK015070 · NIDDK · UNIVERSITY OF CHICAGO · PI ANTONIO C BIANCO, Alexandra Mihaela Dumitrescu · 1986 to 2026
$8.1M
SELENODEIODINAS PROCESSING BY THE PROTEASOME SYSTEMR01DK058538 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BIANCO, ANTONIO C, GEREBEN, BALÁZS · 2001 to 2024
$6.0M
Thyroid-adrenergic synergism and adaptive thermogenesisR01DK065055 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BIANCO, ANTONIO C · 2005 to 2021
$4.4M
Mouse Sbp2 deficiency models the multi-system syndrome of human SBP2 defectsR01DK110322 · NIDDK · UNIVERSITY OF CHICAGO · PI DUMITRESCU, ALEXANDRA MIHAELA · 2016 to 2020
$1.8M
NIDDK NIH HHS R01 DK015070NIDDK NIH HHS R01 DK058538NIDDK NIH HHS R01 DK065055NIDDK NIH HHS R01 DK110322
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mutation, MissenseAdolescentAnimalsChild, PreschoolDNA Mutational AnalysisExome SequencingFemaleGenotypeHEK293 CellsHeredityHumansIodide PeroxidaseKineticsMaleMiceMice, KnockoutIodide Peroxidaseiodothyronine deiodinase type Iselenodeiodinase type 1, mouseTriiodothyronineDIO1elevated rT3mutationthyroid disease

Identifiers

PMID32718224
PMCPMC7891200
OpenAlexW3046087691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.