Evidence map›Paper›PMID 32718152›Full record

ArticlePsychological methods2021

The impact of measurement error and omitting confounders on statistical inference of mediation effects and tools for sensitivity analysis.

Xiao Liu, Lijuan Wang

Abstract read
In one paragraph

Article in Psychological methods, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Estimating latent baseline-by-treatment interactions in statistical mediation analysis.Structural equation modeling : a multidisciplinary journal · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xiao LiuDepartment of Psychology.ORCID 0000-0002-4526-3221
Lijuan WangDepartment of Psychology.

Funding

Efficacy of Family Programs for Improving Child and Family Health and Development.R01HD087319 · NICHD · UNIVERSITY OF NOTRE DAME · PI BRAUNGART-RIEKER, JULIA, CUMMINGS, EDWARD MARK · 2017 to 2021
$3.0M
Pathways Linking Early Adversity and Support to Behavioral and Physical HealthR01HD091235 · NICHD · UNIVERSITY OF NOTRE DAME · PI VALENTINO, KRISTIN · 2018 to 2022
$2.8M
Families of Youth with Developmental Disabilities: A Theory-Based InterventionR01HD088482 · NICHD · UNIVERSITY OF NOTRE DAME · PI CUMMINGS, EDWARD MARK, DIEHL, JOSHUA · 2017 to 2021
$2.7M
NICHD NIH HHS R01 HD087319NICHD NIH HHS R01 HD088482NICHD NIH HHS R01 HD091235NIH HHS
6 · The paper itself

Abstract

To make valid statistical inferences from mediation analysis, a number of assumptions need to be assessed. Among the assumptions, 2 frequently discussed ones are (a) the independent variable, mediator, and outcome variables are measured without error; and (b) no confounders of the effects in the mediation model are omitted. The impact of violating either assumption alone on statistical inference of mediation has been discussed in previous literature. In practice, violations of the 2 assumptions often co-occur. In this study, we analytically investigated the effects of measurement error and omitting confounders on statistical inference of mediation effects, including both point estimation and significance testing. Based on the analytical results, we proposed sensitivity analysis techniques for assessing the robustness of mediation inference to the violation of the 2 assumptions. To implement the techniques, we developed R functions and a user-friendly web tool. Simulated-data and real-data examples were provided for illustrations. We hope the developed tools will help researchers conduct sensitivity analyses of mediation inference more conveniently. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Indexed as

Models, StatisticalNegotiatingHumans

Identifiers

PMID32718152
PMCPMC8351460

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.