Evidence map›Paper›PMID 32718009›Full record

ArticleMicroorganisms2020

Chemically Synthesized

Ken Yoshii, Koji Hosomi, Atsushi Shimoyama, Yunru Wang, Haruki Yamaura, Takahiro Nagatake, Hidehiko Suzuki, Huangwenxian Lan, Hiroshi Kiyono, Koichi Fukase and 1 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The Safety ofViruses · 2026
    Article
  5. Article
  6. Mucosal immunotherapy targeting APC in lung disease.Journal of inflammation (London, England) · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Chemically SynthesizedFrontiers in pharmacology · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Ken YoshiiLaboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka 567-0085, Japan.
Koji HosomiLaboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka 567-0085, Japan.
Atsushi ShimoyamaDepartment of Chemistry, Graduate School of Science, Osaka University, Osaka 560-0043, Japan.ORCID 0000-0003-1910-0450
Yunru WangLaboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka 567-0085, Japan.
Haruki YamauraDepartment of Chemistry, Graduate School of Science, Osaka University, Osaka 560-0043, Japan.
Takahiro NagatakeLaboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka 567-0085, Japan.
Hidehiko SuzukiLaboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka 567-0085, Japan.
Huangwenxian LanLaboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka 567-0085, Japan.
Hiroshi KiyonoInternational Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo (IMSUT), Tokyo 108-8639, Japan.
Koichi FukaseDepartment of Chemistry, Graduate School of Science, Osaka University, Osaka 560-0043, Japan.
Jun KunisawaLaboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka 567-0085, Japan.
National Institute of Biomedical Innovation, Health and Nutrition · JPThe University of Osaka · JPChiba University · JPHiroshima University · JP

Funding

Cross-ministerial Strategic Innovation Promotion Program (SIP; to J.K.)Japan Agency for Medical Research and Development JP17fk0108223h0002 (J.K.), JP17ek0410032s0102 (J.K.), JP17fk0108207h0002 (J.K.), JP17ek0210078h0002 (J.K.), JP17ak0101068h0001 (J.K.), JP17gm1010006s0101 (J.K.), JP18ck0106243h0003 (J.K.) and JP19ek0410062h0001 (J.K.)Japan Society for the Promotion of Science JP15H05836 (K.F.), JP16K01914 (A.S.), JP17K09604 (J.K.), JP18K17997 (K.H.), JP19KK0145 (K.F.), JP20H04776 (A.S.), JP20K05749 (A.S.)Public/Private R&D Investment Strategic Expansion PrograM (PRISM; to J.K.)the Canon Foundation (J.K.)the Joint Research Project of the Institute of Medical Science, the University of Tokyo (J.K.)the Ministry of Health, Labour, and Welfare of Japan JP19KA3001 (J.K. and K.H.)the ONO Medical Research Foundation (J.K.)the Terumo Foundation for Life Sciences and Arts (J.K.)
6 · The paper itself

Abstract

Effective and safe vaccine adjuvants are needed to appropriately augment mucosal vaccine effects. Our previous study demonstrated that lipopolysaccharide (LPS) from Peyer's patch resident

Indexed as

Alcaligenes lipid AIgA antibodyneutrophilpneumococcal surface protein A (PspA), Streptococcus pneumoniaeTh17 response

Identifiers

PMID32718009
PMCPMC7464877
OpenAlexW3044819386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.