Evidence map›Paper›PMID 32717927›Full record

ArticleNutrients2020

Vitamin D Inhibits Myogenic Cell Fusion and Expression of Fusogenic Genes.

Tohru Hosoyama, Hiroki Iida, Minako Kawai-Takaishi, Ken Watanabe

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tohru HosoyamaDepartment of Regenerative Medicine, National Center for Geriatrics and Gerontology, Obu, Aichi 474-8511, Japan.
Hiroki IidaDepartment of Regenerative Medicine, National Center for Geriatrics and Gerontology, Obu, Aichi 474-8511, Japan.
Minako Kawai-TakaishiDepartment of Regenerative Medicine, National Center for Geriatrics and Gerontology, Obu, Aichi 474-8511, Japan.
Ken WatanabeDepartment of Bone and Joint Disease, National Center for Geriatrics and Gerontology, Obu, Aichi 474-8511, Japan.
National Center for Geriatrics and Gerontology · JPNagoya University · JP

Funding

Japan Society for the Promotion of Science 18K09089Ministry of Health, Labour and Welfare 20-2Ministry of Health, Labour and Welfare 29-47Ministry of Health, Labour and Welfare 30-2
6 · The paper itself

Abstract

Vitamin D, a fat-soluble vitamin, is an important nutrient for tissue homeostasis and is recently gaining attention for its role in sarcopenia. Although several studies have focused on the role of vitamin D in muscle homeostasis, the molecular mechanism underlying its action on skeletal muscle remains unclear. This study investigated the role of vitamin D in myogenesis and muscle fiber maintenance in an immortalized mouse myogenic cell line. A high concentration of active vitamin D, 1α,25(OH)

Indexed as

Cell FusionCell LineCell ProliferationGene ExpressionHumansHypertrophyMuscle DevelopmentMuscle, SkeletalMyoblastsSarcopeniaVitamin DVitamin Dcell fusionfusogenic genehypertrophysarcopeniavitamin D

Identifiers

PMID32717927
PMCPMC7469064
OpenAlexW3044362085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.