ArticleAmerican journal of respiratory and critical care medicine2020
Respiratory Tract Dysbiosis Is Associated with Worse Outcomes in Mechanically Ventilated Patients.
Abstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Composition and diversity of the pulmonary microbiome in acute respiratory distress syndrome: a systematic review.Critical care (London, England) · 2025Pooled it
- Impact of Invasive Mechanical Ventilation on the Lung Microbiome.Advances in respiratory medicine · 2025Pooled it
- Airway microbial compartmentalization under mechanical ventilation: a randomized pilot study comparing an endotracheal tube with suction and continuous cuff pressure control (Venner PneuXRespiratory research · 2026Trial
- Trial
- Myeloid cell reprogramming drives enhanced defense againstProceedings of the National Academy of Sciences of the United States of America · 2026Article
- The role of the respiratory microbiome in acute and chronic respiratory diseases.Nature reviews. Microbiology · 2026Review
- Integrating gut‑brain axis insights into bundled nutrition care for critically ill patients: From mechanisms to implementation (Review).Molecular medicine reports · 2026Review
- Review
- Analysis of the pulmonary microbiome in ARDS patients using bronchoalveolar lavage fluid metagenomic next-generation sequencing: a retrospective observational study.Journal of intensive care · 2026Article
- Beyond the Lungs: ICU Oral Care and Gut Resilience-A Hypothesis-Generating Narrative Review.Microorganisms · 2026Review
- Dynamic balance of the lung microbiome in health and respiratory diseases.Chinese medical journal · 2026Review
- Asthma Dysbiosis Index: A Universal Airway Microbiome Signature From Multi-Cohort Analysis.Pediatric pulmonology · 2026Article
- Lower Respiratory Microbiome Dysbiosis Is Associated With Poor Prognosis in Acute Severe Lower Respiratory Tract Infection.MedComm · 2026Article
- The Gut-Lung Microbiome Axis in Alveolar Stem Cell Regeneration and Lung Repair.Microorganisms · 2026Review
- The Role of the Respiratory Microbiome in Pneumonia.Clinics in chest medicine · 2026Review
- Lipid Metabolism and Obesity in Early Life: Drivers of Chronic Lung Disease From Development to Adulthood.Molecular nutrition & food research · 2026Review
- Article
- Indole-acetaldehyde from Rothia mucilaginosa activates the PXR/NRF2 axis to enhance alveolar macrophage phagocytosis and protect against ARDS.Respiratory research · 2026Article
- Microbial lung-to-blood translocation associates with systemic inflammation in severe pneumonia: evidence from paired plasma and lower respiratory tract metagenomics.Intensive care medicine experimental · 2026Article
- Biofilm communities above and below the cuff of endotracheal tubes are spatially homogenous.Respiratory research · 2026Observational
26 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
15 authors.
Georgios D KitsiosDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine and University of Pittsburgh Medical Center.
Haopu YangDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine and University of Pittsburgh Medical Center.
Libing YangDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine and University of Pittsburgh Medical Center.
Shulin QinDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine and University of Pittsburgh Medical Center.
Adam FitchCenter for Medicine and the Microbiome.
Xiao-Hong WangDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine and University of Pittsburgh Medical Center.
Katherine FairDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine and University of Pittsburgh Medical Center.
John EvankovichDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine and University of Pittsburgh Medical Center.
William BainDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine and University of Pittsburgh Medical Center.
Faraaz ShahDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine and University of Pittsburgh Medical Center.
Kelvin LiCenter for Medicine and the Microbiome.
Barbara MethéDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine and University of Pittsburgh Medical Center.
Panayiotis V BenosDepartment of Computational and Systems Biology, and.
Alison MorrisDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine and University of Pittsburgh Medical Center.
Bryan J McVerryDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine and University of Pittsburgh Medical Center.
Funding
Regulation of Cardiolin Byosynthesis in Epithelial InjuryP01HL114453 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RAY, PRABIR · 2014 to 2023
$21.3MGenomic Analysis of Tissue and Cellular Heterogeneity in IPFR01HL127349 · NHLBI · YALE UNIVERSITY · PI BENOS, PANAGIOTIS V, KAMINSKI, NAFTALI · 2015 to 2025
$5.9MSepsis-Associated Immune Suppression and F-box ProteinsR01HL097376 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MALLAMPALLI, RAMA K · 2009 to 2025
$5.1MPathogenesis of Obstruction/Emphysema and the Microbiome (POEM) in HIVU01HL098962 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GHEDIN, ELODIE, MORRIS, ALISON · 2009 to 2013
$3.8MSystems Level Causal Discovery in Heterogeneous TOPMed DataU01HL137159 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BENOS, PANAGIOTIS V, SCIURBA, FRANK · 2017 to 2019
$1.8MINTEGRATIVE GRAPHICAL MODELS FOR LARGE MULTI-MODAL BIOMEDICAL DATAR01LM012087 · NLM · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BENOS, PANAGIOTIS V, GLYMOUR, CLARK · 2015 to 2018
$1.3MMicrobiome-based diagnosis of pneumonia in the acute respiratory distress syndromeK23HL139987 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KITSIOS, GEORGIOS · 2018 to 2022
$806kMetabolic Effects of Early Nutritional Support in Sepsis: A Translational InvestigationK23GM122069 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHAH, FARAAZ ALI · 2016 to 2020
$764kMentoring and Patient-Oriented Research in HIV Obstructive Lung DiseaseK24HL123342 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MORRIS, ALISON · 2014 to 2018
$571kDegradation of The Receptor for Advanced Glycation End Products (RAGE) - A Novel Mechanism in Lung Epithelial Cell InjuryF32HL137258 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI EVANKOVICH, JOHN W · 2017 to 2018
$113kMechanisms of platelet protection in pathogen-triggered lung injuryF32HL142172 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BAIN, WILLIAM G · 2018 to 2019
$103kPlatelet factors attenuate alveolar injury during severe pneumoniaIK2BX004886 · VA · VETERANS HEALTH ADMINISTRATION · PI BAIN, WILLIAM G · 2020 to 2024
–BLRD VA IK2 BX004886NHLBI NIH HHS F32 HL137258NHLBI NIH HHS F32 HL142172NHLBI NIH HHS K23 HL139987NHLBI NIH HHS K24 HL123342NHLBI NIH HHS L30 HL143734NHLBI NIH HHS P01 HL114453NHLBI NIH HHS R01 HL097376NHLBI NIH HHS R01 HL127349NHLBI NIH HHS U01 HL098962NHLBI NIH HHS U01 HL137159NIGMS NIH HHS K23 GM122069NLM NIH HHS R01 LM012087
Abstract
PubMed holds no abstract for this paper.
Indexed as
AdultAgedCritical IllnessDysbiosisFemaleGenetic VariationHumansInflammationMaleMicrobiotaRespiration, ArtificialRespiratory Distress SyndromeRespiratory Systemacute respiratory distress syndromebacterial infectionsendotypesinflammationmicrobiota
Identifiers
What OpenQuestion holds
Textmetadata
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.