Evidence map›Paper›PMID 32717108›Full record

ReviewThe Plant journal : for cell and molecular biology2020

Network-based approaches for understanding gene regulation and function in plants.

Dae Kwan Ko, Federica Brandizzi

Open access · bronzeAbstract readReview
In one paragraph

Review in The Plant journal : for cell and molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
7.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 92 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Improving plant breeding through AI-supported data integration.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Systems genomics of salinity stress response in rice.bioRxiv : the preprint server for biology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Dae Kwan KoMSU-DOE Plant Research Lab, Michigan State University, East Lansing, MI, 48824, USA.ORCID 0000-0002-9720-5138
Federica BrandizziMSU-DOE Plant Research Lab, Michigan State University, East Lansing, MI, 48824, USA.ORCID 0000-0003-0580-8888
Great Lakes Bioenergy Research Center · US

Funding

Unfolded protein response in the model species Arabidopsis thalianaR35GM136637 · NIGMS · MICHIGAN STATE UNIVERSITY · PI Federica Brandizzi · 2020 to 2026
$2.6M
Unfolded protein response in the model species Arabidopsis thalianaR01GM101038 · NIGMS · MICHIGAN STATE UNIVERSITY · PI BRANDIZZI, FEDERICA · 2012 to 2019
$2.5M
NIGMS NIH HHS R01 GM101038NIGMS NIH HHS R35 GM136637NIH HHS GM101038
6 · The paper itself

Abstract

Expression reprogramming directed by transcription factors is a primary gene regulation underlying most aspects of the biology of any organism. Our views of how gene regulation is coordinated are dramatically changing thanks to the advent and constant improvement of high-throughput profiling and transcriptional network inference methods: from activities of individual genes to functional interactions across genes. These technical and analytical advances can reveal the topology of transcriptional networks in which hundreds of genes are hierarchically regulated by multiple transcription factors at systems level. Here we review the state of the art of experimental and computational methods used in plant biology research to obtain large-scale datasets and model transcriptional networks. Examples of direct use of these network models and perspectives on their limitations and future directions are also discussed.

Indexed as

Gene Expression Regulation, PlantGene Regulatory NetworksChromatinChromatin ImmunoprecipitationChromosome MappingComputational BiologyData VisualizationGene Expression ProfilingGenome, PlantModels, GeneticMolecular Sequence AnnotationPlantsChromatingene-regulatory networksmachine learningplantstranscriptional regulation

Identifiers

PMID32717108
PMCPMC8922287
OpenAlexW3045986617

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.