Evidence map›Paper›PMID 32717096›Full record

ArticleChemMedChem2020

Synthesis and Characterization of a Specific Iodine-125-Labeled TRPC5 Radioligand.

Yanbo Yu, Qianwa Liang, Lixia Du, Hao Jiang, Jiwei Gu, Hongzhen Hu, Zhude Tu

Open access · greenAbstract read
In one paragraph

Article in ChemMedChem, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yanbo YuDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Qianwa LiangDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Lixia DuDepartment of Anesthesiology, Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO 63110, USA.
Hao JiangDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Jiwei GuDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Hongzhen HuDepartment of Anesthesiology, Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO 63110, USA.
Zhude TuDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0003-2761-6617
Washington University in St. Louis · US

Funding

PET SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 (S1PR1) RADIOTRACERS FOR MULTIPLE SCLEROSISR01NS103988 · NINDS · WASHINGTON UNIVERSITY · PI Tammie Lee Smith Benzinger, Zhude Tu · 2017 to 2026
$5.3M
PET PROBES FOR IMAGING THE VESICULAR ACETYLCHOLINE TRANSPORTERR01NS075527 · NINDS · WASHINGTON UNIVERSITY · PI TU, ZHUDE · 2011 to 2021
$4.9M
TARGETING THE TRANSIENT RECEPTOR POTENTIAL CHANNELS TO IMPROVE BOWEL DYSFUNCTIONR01DK103901 · NIDDK · WASHINGTON UNIVERSITY · PI HU, HONGZHEN · 2015 to 2023
$3.4M
Neuroinflammatory Biomarkers for Nigrostriatal InjuryR01NS107281 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES · 2019 to 2023
$3.3M
Neuroimaging of PDE10AR01NS103957 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES, TU, ZHUDE · 2017 to 2021
$3.1M
Deciphering the Piezo2-Merkel cell signaling mechanisms in itchR01AR077183 · NIAMS · WASHINGTON UNIVERSITY · PI HU, HONGZHEN · 2020 to 2024
$2.6M
MECHANISMS OF TRPV4-MEDIATED NEUROPATHIC PAINR01AA027065 · NIAAA · WASHINGTON UNIVERSITY · PI HU, HONGZHEN · 2018 to 2022
$2.5M
DEVELOPING PET AGENTS FOR IMAGING PHOSPHODIESTERASE 10A (PDE10A)R33MH092797 · NIMH · WASHINGTON UNIVERSITY · PI TU, ZHUDE · 2013 to 2015
$1.5M
NIAAA NIH HHS R01 AA027065NIAMS NIH HHS R01 AR077183NIDDK NIH HHS R01 DK103901NIMH NIH HHS R33 MH092797NINDS NIH HHS R01 NS075527NINDS NIH HHS R01 NS103957NINDS NIH HHS R01 NS103988NINDS NIH HHS R01 NS107281
6 · The paper itself

Abstract

The nonselective Ca

Indexed as

Radioligand AssayAnimalsBrainCalciumCells, CulturedDose-Response Relationship, DrugHEK293 CellsHumansIodine RadioisotopesMolecular StructurePositron-Emission TomographyRadiopharmaceuticalsRatsTRPC Cation ChannelsCalciumIodine-125Iodine RadioisotopesRadiopharmaceuticalsTRPC5 protein, humanTRPC Cation ChannelsautoradiographyCa2+ imagingiodinePET tracersradioligandsTRPC5

Identifiers

PMID32717096
PMCPMC8544919
OpenAlexW3044020821

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.