Evidence map›Paper›PMID 32716950›Full record

ArticlePloS one2020

Race or racial segregation? Modification of the PM2.5 and cardiovascular mortality association.

Maayan Yitshak-Sade, Kevin J Lane, M Patricia Fabian, Itai Kloog, Jaime E Hart, Brigette Davis, Kelvin C Fong, Joel D Schwartz, Francine Laden, Antonella Zanobetti

Abstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Short-term ambient PMEnvironmental epidemiology (Philadelphia, Pa.) · 2025
    Article
  6. Article
  7. Measuring Spatial Social Polarization in Public Health Research: A Scoping Review of Methods and Applications.Journal of urban health : bulletin of the New York Academy of Medicine · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Evaluating Race in Air Pollution and Health Research: Race, PMCurrent environmental health reports · 2023
    Review
  13. Article
  14. Article
  15. Particulate Air Pollution Exposure and Stroke among Adults in Israel.International journal of environmental research and public health · 2023
    Article
  16. Article
  17. Article
  18. Association between particulate matter air pollution and heart attacks in San Diego County.Journal of the Air & Waste Management Association (1995) · 2021
    Article
  19. The effect of prenatal temperature and PMEnvironment international · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maayan Yitshak-SadeExposure, Epidemiology, and Risk Program, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America.ORCID 0000-0003-4453-0401
Kevin J LaneDepartment of Environmental Health, Boston University School of Public Health, Boston, MA, United States of America.
M Patricia FabianDepartment of Environmental Health, Boston University School of Public Health, Boston, MA, United States of America.
Itai KloogDepartment of Geography and Environmental Development, Faculty of Humanities and Social Sciences, Ben-Gurion University, Beer-Sheva, Israel.
Jaime E HartExposure, Epidemiology, and Risk Program, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America.
Brigette DavisDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America.
Kelvin C FongExposure, Epidemiology, and Risk Program, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America.
Joel D SchwartzExposure, Epidemiology, and Risk Program, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America.
Francine LadenExposure, Epidemiology, and Risk Program, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America.
Antonella ZanobettiExposure, Epidemiology, and Risk Program, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, United States of America.

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
Training Program in Environmental EpidemiologyT32ES007069 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LADEN, FRANCINE · 1985 to 2024
$13.9M
Project 3: Cumulative Risk and Geospatial Health Disparities Related to Chemical and Non-Chemical Stressor ExposuresP50MD010428 · NIMHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI LADEN, FRANCINE, LEVY, JONATHAN I · 2015 to 2020
$4.0M
Cardiovascular Health and Air Pollution: A National StudyR01ES024332 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI ZANOBETTI, ANTONELLA · 2015 to 2018
$2.5M
High Resolution Measures of Behavioral Cancer Risk Factors From Mobile TechnologyR00CA201542 · NCI · HARVARD PILGRIM HEALTH CARE, INC. · PI JAMES, PETER · 2017 to 2019
$747k
NCI NIH HHS R00 CA201542NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES024332NIEHS NIH HHS T32 ES007069NIMHD NIH HHS P50 MD010428
6 · The paper itself

Abstract

backgroundMany studies have identified an inequitable distribution of exposure to PM2.5 (particulate matter less than 2.5 microns) by race. We investigated the association of PM2.5 and cardiovascular mortality considering both the decedents' race and neighborhood racial composition as potential modifiers.

methodsWe obtained geocoded cardiovascular mortality records of all black and white decedents from urban block-groups in Massachusetts between 2001 and 2011 (n = 130,863). We examined the association between PM2.5 and cardiovascular mortality, and assessed effect modification by three types of racial modifiers: decedents' race, census block-group percent black and white, and two novel measures of racial segregation. The Racial Residential Segregation (RRS) quantifies the concentration of non-Hispanic blacks and whites in each block-group. The Index of Racial Dissimilarity measures dissimilarity in non-Hispanic black and white racial distribution between the smaller census block-group and larger tract.

resultsWe found a 2.35%(95%CI: 0.92%;3.79%) increase in mortality for each 10μg/m3 increase in two-day average exposure to PM2.5. The effect was modified by the block-group racial composition, with higher risks in block-groups with the highest percentage of black residents (interaction p-value = 0.04), and in block-groups with the lowest RRS (i.e. higher black to white resident ratio, interaction p-value = 0.072). Racial dissimilarity did not modify the associations.

conclusionCurrent levels of PM2.5 are associated with increased cardiovascular deaths in Massachusetts, with different risks between areas with different racial composition and segregation. This suggests that pollution reductions in neighborhoods with the highest percentage of non-Hispanic blacks would be most beneficial in reducing cardiovascular mortality and disparities.

Indexed as

Particle SizeRacial GroupsSocial SegregationAged, 80 and overCardiovascular DiseasesFemaleHumansMaleParticulate MatterRisk FactorsStatistics as TopicUrban PopulationParticulate Matter

Identifiers

PMID32716950
PMCPMC7384646

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.