Evidence map›Paper›PMID 32716523›Full record

ReviewJournal of oral rehabilitation2021

Medications and addictive substances potentially inducing or attenuating sleep bruxism and/or awake bruxism.

Cees de Baat, Merel C. Verhoeff, Jari Ahlberg, Daniele Manfredini, Ephraim Winocur, Petra Zweers, Fred Rozema, Arjan Vissink, Frank Lobbezoo

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of oral rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
15.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 117 citations in OpenAlex.

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  16. Exploring the Role of Oral Microbiota in the Pathophysiology and Treatment of Bruxism.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 4 countries.

Cees de BaatFoundation for Oral Health and Parkinson's Disease, Oegstgeest, The Netherlands.ORCID 0000-0002-5580-2647
Merel C. VerhoeffDepartment of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Jari AhlbergDepartment of Oral and Maxillofacial Diseases, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-6052-0441
Daniele ManfrediniDepartment of Biomechanical Diseases, School of Dentistry, University of Siena, Siena, Italy.ORCID 0000-0002-4352-3085
Ephraim WinocurDepartment of Oral Rehabilitation, Dental School, Tel Aviv University, Tel Aviv, Israel.
Petra ZweersNetherlands pharmacovigilance centre LAREB, Hertogenbosch, The Netherlands.
Fred RozemaDepartment of Oral Medicine, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Arjan VissinkDepartment of Oral and Maxillofacial Surgery, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
Frank LobbezooFoundation for Oral Health and Parkinson's Disease, Oegstgeest, The Netherlands.ORCID 0000-0001-9877-7640
Academic Center for Dentistry Amsterdam · NLNetherlands Pharmacovigilance Centre Lareb · NLRadboud University Nijmegen · NLTel Aviv University · ILUniversity Medical Center Groningen · NLUniversity of Helsinki · FIUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bruxism is a repetitive jaw-muscle activity characterised by clenching or grinding of the teeth and/or by bracing or thrusting of the mandible. It can occur during sleep, indicated as sleep bruxism, or during wakefulness, indicated as awake bruxism. Exogenous risk indicators of sleep bruxism and/or awake bruxism are, among others, medications and addictive substances, whereas also several medications seem to have the potential to attenuate sleep bruxism and/or awake bruxism. The objective of this study was to present a narrative literature on medications and addictive substances potentially inducing or aggravating sleep bruxism and/or awake bruxism and on medications potentially attenuating sleep bruxism and/or awake bruxism. Literature reviews reporting evidence or indications for sleep bruxism and/or awake bruxism as an adverse effect of several (classes of) medications as well as some addictive substances and literature reviews on medications potentially attenuating sleep bruxism and/or awake bruxism were used as starting point and guidelines to describe the topics mentioned. Additionally, two literature searches were established on PubMed. Three types of bruxism were distinguished: sleep bruxism, awake bruxism and non-specified bruxism. Generally, there are insufficient evidence-based data to draw definite conclusions concerning medications and addictive substances inducing or aggravating sleep bruxism and/or awake bruxism as well as concerning medications attenuating sleep bruxism and/or awake bruxism. There are insufficient evidence-based data to draw definite conclusions concerning medications and addictive substances inducing or aggravating sleep bruxism and/or awake bruxism as well as concerning medications attenuating sleep bruxism and/or awake bruxism.

Indexed as

BruxismSleep BruxismSubstance-Related DisordersHumansSleepWakefulnessaddictiveadverse effectattenuating effectawake bruxismmedicationsleep bruxism

Identifiers

PMID32716523
PMCPMC7984358
OpenAlexW3045604289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.