Evidence map›Paper›PMID 32715668›Full record

ArticleJournal of Korean medical science2020

Similar Durability of Two Single Tablet Regimens, Dolutegravir/Abacavir/Lamivudine and Elvitegravir/Cobicistat/Tenofovir/Emtricitabine: Single Center Experience.

Bum Sik Chin, Jin Hee Lee, Gayeon Kim

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Bum Sik ChinDivision of Infectious Diseases, Department of Internal Medicine, National Medical Center, Seoul, Korea. moberrer@nmc.or.kr.ORCID https://orcid.org/0000-0003-3021-1434
Jin Hee LeeLaboratory for Future Emergency Medical Service, National Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-2556-5484
Gayeon KimDivision of Infectious Diseases, Department of Internal Medicine, National Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0001-9788-9800
National Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integrase inhibitor is uniquely available as single tablet regimen (STR) in Korea. In this study, the durability until 96 weeks was compared between dolutegravir/abacavir/lamivudine (D/A/L) and elvitegravir/cobicistat/tenofovir/emtricitabine (E/T/E) in treatment naïve human immunodeficiency virus 1 (HIV-1) infected individuals. From 2014 to 2017, 153 and 234 subjects started D/A/L and E/T/E, respectively. During 96 weeks, 73 discontinued initial STR and the reason of discontinuation was typable in 44. The frequency of drug adverse event related discontinuation (AEDC) was higher in D/A/L (13.1% vs. 6.4%,

Indexed as

AbacavirAntineoplastic Combined Chemotherapy ProtocolsCentral Nervous System DiseasesCobicistatDideoxynucleosidesDolutegravirDrug Administration ScheduleEmtricitabineHeterocyclic Compounds, 3-RingHIV InfectionsHumansLamivudineOxazinesPiperazinesPyridonesQuinolonesAbacavirCobicistatDideoxynucleosidesDolutegravirelvitegravirEmtricitabineHeterocyclic Compounds, 3-RingLamivudineOxazinesPiperazinesPyridonesQuinolonesTabletsTenofovirAntiretroviral TherapiesDurabilityIntegrase InhibitorsSingle Tablet Regimen

Identifiers

PMID32715668
PMCPMC7384898
OpenAlexW3038077741

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.