Evidence map›Paper›PMID 32715607›Full record

ArticlePediatric obesity2021

Sex-based differences in screening and recognition of pre-diabetes and type 2 diabetes in pediatric primary care.

Mary Ellen Vajravelu, Joyce M Lee, Sandra Amaral, Andrea Kelly

Abstract read
In one paragraph

Article in Pediatric obesity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mary Ellen VajraveluDivision of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-5839-7923
Joyce M LeeDivision of Pediatric Endocrinology, Susan B Meister Child Health Evaluation and Research Center, University of Michigan, Ann Arbor, Michigan, USA.
Sandra AmaralDivision of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Andrea KellyDivision of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Funding

Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
Cardiometabolic Health in Adolescents of South Asian Ancestry - the CHAriSmA studyR01DK115648 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI MAGGE, SHEELA NATESH · 2018 to 2022
$3.9M
Career Development Program in Pediatric Diabetes Research (K12) at CHOPK12DK094723 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI WILLI, STEVEN M · 2011 to 2020
$3.6M
Urological and Renal Disease Engaging Adolescents in Adherence Collaborative TrialR01DK110749 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI AMARAL, SANDRA · 2016 to 2020
$3.5M
Reaching Equity for Adults and CHildren in Transplant (REACH-TRANSPLANT)R01DK120886 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AMARAL, SANDRA, KU, ELAINE · 2019 to 2023
$3.5M
VIRTUUS Children's Study: Validating Injury to the Renal Transplant Using Urinary Signatures in ChildrenR01HD091185 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI AMARAL, SANDRA, KEATING, BRENDAN JAMES · 2017 to 2021
$3.4M
Conventional and Metabolomic Predictors of Pediatric Prediabetes & Insulin ResistR01HD074559 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEE, JOYCE · 2014 to 2018
$2.7M
Target self-regulation to promote adherence and health behaviors in childrenUH3HD087979 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FREDERICKS, EMILY MACDONALD, MILLER, ALISON L · 2018 to 2019
$2.1M
Evaluation of the entero-insular (incretin) axis in cystic fibrosis-competitive renewal.R56DK097830 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI KELLY, ANDREA BRIDGET, RICKELS, MICHAEL R · 2019 to 2019
$147k
Juvenile Diabetes Research FoundationNICHD NIH HHS R01 HD074559NICHD NIH HHS R01HD074559NICHD NIH HHS R01 HD091185NICHD NIH HHS R01HD091185NICHD NIH HHS UH3 HD087979NICHD NIH HHS UH3HD087979NIDDK NIH HHS 2R56 DK97830-06NIDDK NIH HHS 5K12DK094723-08NIDDK NIH HHS K12 DK094723NIDDK NIH HHS P30 DK092926NIDDK NIH HHS R01 DK110749NIDDK NIH HHS R01DK110749NIDDK NIH HHS R01 DK115648NIDDK NIH HHS R01DK115648NIDDK NIH HHS R01 DK120886NIDDK NIH HHS R01DK120886NIDDK NIH HHS R56 DK097830
6 · The paper itself

Abstract

backgroundRisk-based screening for type 2 diabetes (T2D) in youth with overweight/obesity is recommended, but rates remain low in practice. Identification of factors impacting provider ordering and patient completion of testing may guide strategies to improve screening.

objectiveTo evaluate predictors of hemoglobin A1c (A1c)-based T2D screening in pediatric primary care.

methodsThis retrospective cohort study included 10 to 18 year-old patients with overweight/obesity (body mass index [BMI] Z-score ≥1.04) followed in a large academic-affiliated pediatric primary care network, 2009 to 2018. Percentages of patients with ordered and completed A1c were determined, and multivariable Cox proportional hazards regression was used to evaluate independent predictors of screening.

results34 927 (48.0% female; 52.5% with BMI Z-score ≥1.64) youth followed for a median of 3.0 years were included. 21% (7457) of patients had screening ordered and 14% (4966) completed screening during follow-up. In multivariable regression, after controlling for race/ethnicity, BMI, family history of diabetes and age, males were significantly less likely to have ordered screening, but were equally or more likely to complete screening if ordered.

conclusionsMale adolescents were less likely to undergo A1c-based T2D screening due to differential ordering practices. The source of this differential practice should be pursued to avoid under-recognition of cardiometabolic risk in at-risk male youth.

Indexed as

AdolescentBiomarkersChildDiabetes Mellitus, Type 2FemaleFollow-Up StudiesGlycated HemoglobinGuideline AdherenceHealthcare DisparitiesHumansMaleMass ScreeningPatient CompliancePediatric ObesityPediatricsPractice Guidelines as TopicBiomarkersGlycated Hemoglobinhemoglobin A1c protein, humanadolescentbody mass indexglycated hemoglobin aobesityoverweight

Identifiers

PMID32715607
PMCPMC7790878

What OpenQuestion holds

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LicenceTDM
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.