Evidence map›Paper›PMID 32715407›Full record

ArticleMolecular and cellular biochemistry2020

The comparison of the effects of ketamine and etomidate on cardiodynamics, biochemical and oxidative stress parameters in Wistar male rats.

M Djuric, S Kostic, T Nikolic Turnic, S Stankovic, R Skrbic, D M Djuric, V Zivkovic, V Jakovljevic, P Stevanovic

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

M DjuricDepartment of Anesthesiology, Reanimatology and Intensive Care Medicine, University Clinical Hospital Center "Dr. Dragisa Misovic - Dedinje", Belgrade, Serbia.
S KosticFaculty of Medicine, University of Belgrade, Belgrade, Serbia.
T Nikolic TurnicDepartment of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
S StankovicCentre of Medical Biochemistry, Clinical Centre of Serbia, Belgrade, Serbia.
R SkrbicDepartment of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine, University of Banja Luka, Banja Luka, Bosnia and Herzegovina.
D M DjuricInstitute of Medical Physiology "Richard Burian", Faculty of Medicine, University of Belgrade, Visegradska 26/2, 11000, Belgrade, Serbia. drdjuric@eunet.rs.
V ZivkovicDepartment of Physiology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
V JakovljevicDepartment of Physiology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
P StevanovicDepartment of Anesthesiology, Reanimatology and Intensive Care Medicine, University Clinical Hospital Center "Dr. Dragisa Misovic - Dedinje", Belgrade, Serbia.
University of Kragujevac · RSUniversity Hospital Center Dr Dragiša Mišović · RSUniversity of Belgrade · RSUniversity of Banja Luka · BA

Funding

Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja OI175043
6 · The paper itself

Abstract

It is well known the use of ketamine and etomidate in clinical practice; however, the difference in the systemic effects of these two anesthetic agents is still debatable. Thus, in the present study we aimed to compare their effects on heart, and other organs through estimation of cardiodynamics, biochemical and hematological parameters. Male Wistar rats were divided in 2 groups containing of 2 subgroups (n = 7 in each subgroup, n = 28 in total): (1) bolus injection of anesthetic ketamine (40 mg/kg b.w., i.p. n = 14); (2) bolus injection of anesthetic etomidate (20 mg/kg b.w., i.p. n = 14). The experiments were done in vitro in one subgroup of each group: cardiodynamic variables (dp/dt

Indexed as

Anesthetics, DissociativeAnesthetics, IntravenousAnimalsCardiovascular Physiological PhenomenaEtomidateHeartKetamineMaleOxidative StressRatsRats, WistarAnesthetics, DissociativeAnesthetics, IntravenousEtomidateKetamineAnestheticsBiochemical parametersCardiodynamicsEtomidateHematological parametersKetamineOxidative stressRat

Identifiers

PMID32715407
OpenAlexW3045136891

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.