ArticleNeurosurgical review2021
Retrospective application of risk scores to ruptured intracranial aneurysms: would they have predicted the risk of bleeding?
Article in Neurosurgical review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Pooled it
- Novel Morphological Classification of Intracranial Aneurysm Wall Irregularity Associates Specific Features with Increased Size and Rupture Risk: A Retrospective Single-Center Cross-Sectional Study.Neurology international · 2026Article
- Predictors of Outcome Clusters in Patients With Unruptured Intracranial Aneurysms Treated With Microsurgery: An Unsupervised Machine Learning Analysis.Neurosurgery practice · 2026Article
- Association of erythrocyte fatty acid profiles with the presence and rupture of intracranial aneurysms.Lipids in health and disease · 2026Article
- In Vivo Deformation of the Human Basilar Artery.Annals of biomedical engineering · 2025Article
- Retrospective Application of Risk Scores to Unruptured Anterior Communicating Artery Aneurysms.Journal of clinical medicine · 2024Article
- Unruptured intracranial aneurysms: Why should we focus on small aneurysms? A comprehensive update of recent findings.Polish journal of radiology · 2024Review
- An overview of decision-making in cerebrovascular treatment strategies: Part I - unruptured aneurysms.Brain & spine · 2024Review
- Enhancing intracranial aneurysm rupture risk prediction with a novel multivariable logistic regression model incorporating high-resolution vessel wall imaging.Frontiers in neurology · 2024Article
- Clinical Scales in Aneurysm Rupture Prediction.Stroke (Hoboken, N.J.) · 2024Review
- Circumferential wall enhancement with contrast ratio measurement in unruptured intracranial aneurysm for aneurysm instability.Brain and behavior · 2022Article
- Computer-Assisted Aneurysm Growth Evaluation and Detection (AGED): Comparison with Clinical Aneurysm Follow-Up.Journal of blood disorders & transfusion · 2022Article
- Machine Learning and Intracranial Aneurysms: From Detection to Outcome Prediction.Acta neurochirurgica. Supplement · 2022Article
- Risk factors for the progression of unruptured intracranial aneurysms in patients followed by CT/MR angiography.Quantitative imaging in medicine and surgery · 2021Article
- Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As the incidental diagnosis of unruptured intracranial aneurysms has been increasing, several scores were developed to predict risk of rupture and growth to guide the management choice. We retrospectively applied these scores to a multicenter series of patients with subarachnoid hemorrhage to test whether they would have predicted the risk of bleeding in the event of aneurysm discovery previous to its rupture. Demographical, clinical, and radiological information of 245 adults were retrieved from two neurovascular centers' database. Data were pooled and PHASES, UCAS, and ELAPSS scores were retrospectively calculated for the whole population and their performances in identifying aneurysms at risk of rupture were compared. Mean PHASES, UCAS, and ELAPSS scores were 5.12 ± 3.08, 5.09 ± 2.62, and 15.88 ± 8.07, respectively. Around half (46%) of patients would have been assigned to the low- or very low-risk class (5-year rupture risk < 1%) in PHASES. Around 28% of patients would have been in a low-risk class, with a probability of 3-year rupture risk < 1% according to UCAS. Finally, ELAPSS score application showed a wider distribution among the risk classes, but a significant proportion of patients (45.5%) lie in the low- or intermediate-risk class for aneurysm growth. A high percentage of patients with ruptured aneurysms in this multicenter cohort would have been assigned to the lower risk categories for aneurysm growth and rupture with all the tested scores if they had been discovered before the rupture. Based on these observations, physicians should be careful about drawing therapeutic conclusions solely based on application of these scores.
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