Evidence map›Paper›PMID 32715157›Full record

ArticleAmerican journal of ophthalmology case reports2020

Yet another case of ocular sarcoidosis.

Doan Luong Hien, Neil Onghanseng, Than Trong Tuong Ngoc, Jaclyn Joyce Hwang, Brandon Huy Pham, Huy Luong Doan, Huy V Nguyen, Muhammad Sohail Halim, Gunay Uludag, Yasir J Sepah and 2 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of ophthalmology case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Fungal Endophthalmitis Secondary toJournal of vitreoretinal diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Doan Luong HienByers Eye Institute, Stanford University, Palo Alto, CA, USA.
Neil OnghansengByers Eye Institute, Stanford University, Palo Alto, CA, USA.
Than Trong Tuong NgocByers Eye Institute, Stanford University, Palo Alto, CA, USA.
Jaclyn Joyce HwangByers Eye Institute, Stanford University, Palo Alto, CA, USA.
Brandon Huy PhamByers Eye Institute, Stanford University, Palo Alto, CA, USA.
Huy Luong DoanKansas City University of Medicine and Biosciences, Kansas City, MO, USA.
Huy V NguyenByers Eye Institute, Stanford University, Palo Alto, CA, USA.
Muhammad Sohail HalimByers Eye Institute, Stanford University, Palo Alto, CA, USA.
Gunay UludagByers Eye Institute, Stanford University, Palo Alto, CA, USA.
Yasir J SepahByers Eye Institute, Stanford University, Palo Alto, CA, USA.
Diana V DoByers Eye Institute, Stanford University, Palo Alto, CA, USA.
Quan Dong NguyenByers Eye Institute, Stanford University, Palo Alto, CA, USA.
Smith-Kettlewell Eye Research Institute · USPham Ngoc Thach University of Medicine · VNKansas City University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report a case of bilateral pan-uveitis resembling fungal and viral endophthalmitis in a patient who was ultimately diagnosed with sarcoidosis. OBSERVATION: A 64-year-old female presented with a four-day history of painless vision loss in the right eye. She presented with multiple concurrent systemic complaints, including a history of oral and genital sores, patches of hypopigmented skin on her forearms, and occasional shortness of breath. Upon further examination, she was noted to have bilateral pan-uveitis, which was more severe in the right than left eye. Posterior pole examination of the right eye revealed dense vitritis with multiple large whitish round balls that seemed suggestive of fungal or viral endophthalmitis. Initial therapies included intravitreal (IVT) foscarnet and intravenous (IV) acyclovir, followed by IV amphotericin B and oral voriconazole, which did not improve ocular signs and symptoms. Further evaluations ruled out infectious etiologies and lymphoma. Chest computerized tomography (CT) scan revealed findings suggestive of sarcoidosis, which was confirmed with lung biopsy. Anti-viral and -fungal treatments were discontinued, and the patient was started on IV methylprednisolone followed by oral prednisone and mycophenolate mofetil. Ocular symptoms improved, and the patient remained stable after treatment. CONCLUSION AND IMPORTANCE: The index report illustrates a case of ocular sarcoidosis that imitated the presentation of infectious endophthalmitis. Though ocular sarcoidosis is known to masquerade as a range of disorders and constitutes part of the differential diagnosis for infectious endophthalmitis, sarcoidosis has not been reported in recent literature to imitate the presentation of fungal endophthalmitis. The index case suggests that ocular sarcoidosis should be considered in the differential diagnoses of fungal endophthalmitis.

Indexed as

Fungal endophthalmitisInfectious endophthalmitisMimickingPan-uveitisSarcoidosisVitreous balls

Identifiers

PMID32715157
PMCPMC7372148
OpenAlexW3041017052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.