ArticleHeliyon2020
Kratom instrumentalization for severe pain self-treatment resulting in addiction - A case report of acute and chronic subjective effects.
Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- The addictive and neurotoxicological evaluation ofIBRO neuroscience reports · 2025Article
- [Kratom-From natural remedy to addictive drug and back].Der Nervenarzt · 2024Review
- Knowledge of Kratom among Alabama Pharmacists.Pharmacy (Basel, Switzerland) · 2023Article
- Kratom availability in California vape shops.Preventive medicine reports · 2023Article
- The modulatory effects of alkaloid extracts of Cannabis sativa, Datura stramonium, Nicotiana tabacum and male Carica papaya on neurotransmitter, neurotrophic and neuroinflammatory systems linked to anxiety and depression.Inflammopharmacology · 2022Article
- [Kratom - a short review for pain medicine].Schmerz (Berlin, Germany) · 2022Review
- Searching for a Signal: Self-Reported Kratom Dose-Effect Relationships Among a Sample of US Adults With Regular Kratom Use Histories.Frontiers in pharmacology · 2022Article
- Kratom use for depression/anxiety self-management: challenges during the COVID-19 pandemic - A case report.Heliyon · 2021Article
- Case Report: Treatment of Kratom Use Disorder With a Classical Tricyclic Antidepressant.Frontiers in psychiatry · 2021Article
- Mitragynine (Kratom)-Induced Cognitive Impairments in Mice Resemble Δ9-THC and Morphine Effects: Reversal by Cannabinoid CBFrontiers in pharmacology · 2021Article
- Methadone, Buprenorphine, and Clonidine Attenuate Mitragynine Withdrawal in Rats.Frontiers in pharmacology · 2021Article
- Can Kratom (Frontiers in psychiatry · 2020Article
- An update on the clinical pharmacology of kratom: uses, abuse potential, and future considerations.Expert review of clinical pharmacologyReview
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundKratom is a Southeast Asian plant, which is widely used in this region, and making an increasing appearance in Europe and the US. CASE REPORT: We present the case of a 26-year-old man in Substitol-assisted treatment of excessive Kratom and Tilidin use expressing the wish for a drug-free management of a chronic pain condition. After an accidental calcaneus impression fracture, the patient was suffering from severe chronic pain and anxiety of further accidents. This was managed initially with Tilidin. Resulting from the wish to self-manage the pain condition in a way that permitted continuation of a job, the patient searched for a 'natural' treatment alternative obtained from an Internet vendor. He successfully instrumentalized Kratom for 3 years with daily consumption intermixed with occasional Tilidin for pain management. However, the dose of Kratom was increased considerably up to a level of effect reversal, when no analgesic and behaviorally activating effects occurred any more, but only intense drowsiness. The patient was treatment seeking and subsequently detoxified from Kratom and Tilidin. Pain management was shifted to retarded morphine.
conclusionKratom instrumentalization for pain management might appear to be more problematic for addiction development than when its use is established for other consumption motives.
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