ArticleClinical and translational radiation oncology2020
Conventionally fractionated large volume head and neck re-irradiation using multileaf collimator-based robotic technique: A feasibility study.
Article in Clinical and translational radiation oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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- Clinical application of a GPU-accelerated monte carlo dose verification for cyberknife M6 with Iris collimator.Radiation oncology (London, England) · 2024Article
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4 authors at 2 institutions in 3 countries.
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Abstract
purposeTo report on the feasibility and performance of conventionally fractionated multileaf collimator (MLC)-based robotic stereotactic body re-irradiation of the head and neck region using MLC-based Cyberknife (CK) technology.
methodsPatients treated for recurrent or second primary head and neck cancer (HNC) with curative proton therapy to a target volume > 30 cm
resultsEight patients were included; the tumor sites included: salivary glands, pharynx (oropharynx, hypopharynx and retropharynx) and sinonasal cavities. Five of 8 patients were treated with multifield optimisation intensity modulated proton therapy, 3 were treated with passive scattering proton therapy. Median dose was 67 Gy (range 60-70) in 32 fractions (range 30-35). The median high-dose planning target volume (PTV) was 45.4 cm
conclusionOur study has demonstrated the dosimetric performance of large volume head and neck re-irradiation using MLC-based CK in various clinical scenarios. While conformity was generally better achieved with PBT, MLC-based CK allowed for high dose gradient leading to rapid dose drop-off and sparing of OAR. Conventionally fractionated MLC-based CK could be a competitive alternative in large volume head and neck re-irradiation that deserves further investigation in the clinical setting.
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