Evidence map›Paper›PMID 32714876›Full record

ArticleFrontiers in cellular and infection microbiology2020

Anti-inflammatory Role of Galectin-8 During

Adriano Bertelli, Liliana M Sanmarco, Carla A Pascuale, Miriam Postan, Maria P Aoki, María S Leguizamón

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Galectin-8 deficiency promotes chronic splenomegaly persistence in Chagas disease.Frontiers in cellular and infection microbiology · 2025
    Article
  5. Review
  6. The role of galectins in immunity and infection.Nature reviews. Immunology · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Adriano BertelliInstituto de Investigaciones Biotecnológicas, Universidad Nacional de General San Martín, San Martín, Argentina.
Liliana M SanmarcoConsejo Naciona de Investigaciones Científicas y Tecnológicas, Buenos Aires, Argentina.
Carla A PascualeInstituto de Investigaciones Biotecnológicas, Universidad Nacional de General San Martín, San Martín, Argentina.
Miriam PostanConsejo Naciona de Investigaciones Científicas y Tecnológicas, Buenos Aires, Argentina.
Maria P AokiConsejo Naciona de Investigaciones Científicas y Tecnológicas, Buenos Aires, Argentina.
María S LeguizamónInstituto de Investigaciones Biotecnológicas, Universidad Nacional de General San Martín, San Martín, Argentina.
National University of General San Martín · ARUniversidad Nacional de Córdoba · ARAdministración Nacional de Laboratorios e Institutos de Salud · ARCentro Científico Tecnológico - San Juan · AR

Funding

Role in pathogenesis and parasite cell biology of the trans-sialidase from Trypanosoma cruzi, the agent of Chagas DiseaseR01AI104531 · NIAID · INSTITUTE/RESEARCH/BIOTECHNOLOGY FDN · PI CAMPETELLA, OSCAR EDUARDO · 2014 to 2023
$1.3M
NIAID NIH HHS R01 AI104531
6 · The paper itself

Abstract

Galectins are animal lectins with high affinity for β-galactosides that drive the immune response through several mechanisms. In particular, the role of galectin-8 (Gal-8) in inflammation remains controversial. To analyze its role in a chronic inflammatory environment, we studied a murine model of

Indexed as

Chagas DiseaseTrypanosoma cruziAnimalsAnti-Inflammatory AgentsDisease Models, AnimalGalectinsMiceMice, Inbred C57BLMice, KnockoutAnti-Inflammatory Agentsgalectin-8, mouseGalectinsChagas diseasefibrosisinflammationneutrophilspreaparesis

Identifiers

PMID32714876
PMCPMC7343849
OpenAlexW3040451357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.