ArticlePeerJ2020
Prognostic value of complementary biomarkers of neurodegeneration in a mixed memory clinic cohort.
Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- Non-invasive neuromodulation in reducing the risk of falls and fear of falling in community-dwelling older adults: systematic review.Frontiers in aging neuroscience · 2023Pooled it
- Prognostic value of light reflex pupillometry in Alzheimer's disease - a longitudinal cohort study.Alzheimer's research & therapy · 2025Article
- Different effect of hypo- and hypermetabolism on cognition in dementia with Lewy bodies: are they coupled or independent?NPJ Parkinson's disease · 2024Article
- Utility of the Comprehensive Trail Making Test in the Assessment of Mild Cognitive Impairment in Older Patients.Geriatrics (Basel, Switzerland) · 2023Article
- Diagnostic performance of light reflex pupillometry in Alzheimer's disease.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBiomarkers of neurodegeneration, e.g. MRI brain atrophy and [
objectiveOur primary objective was to investigate prognostic properties of atrophy and hypometabolism.
methodsFrom March 2015-June 2016, 149 patients referred to a university hospital memory clinic were included. The primary outcome was progression/stable disease course as assessed by a clinician at 12 months follow-up. Intracohort defined
resultsMedian follow-up time was 420 days [IQR: 387-461 days] and 50 patients progressed. Patients with two or more lobes affected by the pattern +A/+H compared to patients with 0-1 lobes affected had a statistically significant increased risk of progression (odds ratio, 95 % confidence interval: 4.33, 1.90-9.86) in a multivariable model. The model was partially robust to the applied sensitivity analysis.
conclusionCombined atrophy and hypometabolism as assessed by MRI and [
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.