Evidence map›Paper›PMID 32714563›Full record

ArticleCell discovery2020

Sulfated polysaccharides effectively inhibit SARS-CoV-2 in vitro.

Paul S Kwon, Hanseul Oh, Seok-Joon Kwon, Weihua Jin, Fuming Zhang, Keith Fraser, Jung Joo Hong, Robert J Linhardt, Jonathan S Dordick

Registry-linked trialAbstract readLetter
In one paragraph

Article in Cell discovery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05729204 (Washing COVID-19 Away With a Hypertonic Seawater Nasal Irrigation Solution Containing Algal and Herbal Natural Ingredients), which is not on this map. Cited by 175 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
175citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05729204 nacompletednot on this mapstarted 2022, after this paper: background citation

Washing COVID-19 Away With a Hypertonic Seawater Nasal Irrigation Solution Containing Algal and Herbal Natural Ingredients

TypeinterventionalSponsorLarissa University HospitalRan2022 to 2022Enrolled56ConditionsSARS-CoV2 InfectionArmsHypertonic seawater solution
3 · Its place in the literature

Who cites it

175 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
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  7. Review
  8. Review
  9. Article
  10. Article
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  14. Polysialosides Outperform Sulfated Analogs for Binding with SARS-CoV-2.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  15. Review
  16. Article
  17. Efficacy of hypertonic nasal spray with algae in rhinosinusitis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Observational
  18. Article
  19. Article
  20. Review

115 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Paul S Kwon *Department of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY USA.
Hanseul Oh *National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, Chungcheongbuk Republic of Korea.
Seok-Joon Kwon *Department of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY USA.
Weihua JinDepartment of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY USA.
Fuming ZhangDepartment of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY USA.
Keith FraserDepartment of Biological Sciences, Rensselaer Polytechnic Institute, Troy, NY USA.
Jung Joo HongNational Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, Chungcheongbuk Republic of Korea.ORCID 0000-0002-9795-6513
Robert J LinhardtDepartment of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY USA.ORCID 0000-0003-2219-5833
Jonathan S DordickDepartment of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY USA.ORCID 0000-0001-7802-3702

Funding

Korea Research Institute of Bioscience and Biotechnology (KRIBB) KGM4572013
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GlycobiologyMechanisms of disease

Identifiers

PMID32714563
PMCPMC7378085

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.