ArticleAnnals of medicine and surgery (2012)2020
Effects of thyroid dysfunction on hematological parameters: Case controlled study.
Article in Annals of medicine and surgery (2012), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 70 citations in OpenAlex.
- The Role of Immunological Challenges, Oxidative Stress, and Dietary Interventions in Managing Hashimoto's Thyroiditis: A Narrative Review.Nutrition reviews · 2026Review
- Prevalence and determinants of anemia in hypothyroidism and hyperthyroidism at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.BMC endocrine disorders · 2026Article
- Phenotypic Age Acceleration as a Mediator in Thyroid Hormone-Related Cardiovascular Risk Among the Elderly.Cardiology research and practice · 2026Article
- The impact of hyperthyroidism on the hematopoietic system.Clinical and experimental medicine · 2025Article
- Association Between Complete Blood Count and the Lipoxygenase Pathway in Hashimoto's Thyroiditis.Cells · 2025Article
- An Atlas of Genetic Correlations Between Thyroid Hormone Levels and Human Health-Related Traits.Health science reports · 2025Article
- A Prospective Study on Anemia in Hypothyroidism and Hyperthyroidism.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Article
- Development and validation of a nomogram for predicting immune-related thyroid dysfunction during immunotherapy in non-small cell lung cancer: a prospective cohort study in China.Frontiers in immunology · 2025Article
- Association between thyroid hormone levels and hematological indices among women with thyroid disorders.Qatar medical journal · 2025Article
- Assessing thyroid health: phenotypic age compared to chronological age.Frontiers in endocrinology · 2025Article
- Hematological changes in women with cervical cancer before and after cancer treatment: retrospective cohort study.Scientific reports · 2024Article
- Changes in Erythrocytes in 88 Hyperthyroid Cats.Animals : an open access journal from MDPI · 2024Article
- Essential New Complexity-Based Themes for Patient-Centered Diagnosis and Treatment of Dementia and Predementia in Older People: Multimorbidity and Multilevel Phenomenology.Journal of clinical medicine · 2024Review
- Bidirectional Association between Periodontitis and Thyroid Disease: A Scoping Review.International journal of environmental research and public health · 2024Article
- Article
- Hematological Abnormalities and Associated Factors Among Patients with Hypothyroidism at the University of Gondar Comprehensive Specialized Hospital.Journal of blood medicine · 2024Article
- Hematological Indices in Patients With Goiter: A Cross-Sectional Study in a Tertiary Care Hospital in South India.Cureus · 2023Article
- Is Restless Legs Syndrome De Facto Thyroid Disease?Biomedicines · 2022Article
- Machine learning identifies baseline clinical features that predict early hypothyroidism in patients with Graves' disease after radioiodine therapy.Endocrine connections · 2022Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe thyroid gland has a very important role in hematopoiesis, blood disorders are frequently seen in patients with thyroid disorders. Thyroid hormones have direct effect on blood parameters by stimulating erythrocytes precursors and indirectly by enhancing erythropoietin production. PATIENTS AND
methodsThis is a case-control study which included 300 subjects who were grouped to 3 equal groups as a control, hypothyroidism, and hyperthyroidism groups. Patients with inherited or acquired red cell abnormalities, those receiving treatment for thyroid disorder or anemia, patient with chronic diseases, aged <12 years, pregnant ladies and patients unwilling to participate in the study were excluded.
resultsThe mean age of patients is 40.72 years, and females constituted 60.7% of cases. The analyses showed a significant difference the RBC, HB, MCV, MCHC, RDW, and WBC (P values 0.000, 0.000, 0.001, 0.012.0.002, and 0.027) respectively, while platelets showed no significant correlation (P value 0.08). The univariate analyses showed that RBC, the HB, and the WBC were the most severely affected parameters (Sig. 0.000, 0.000, and 0.005) respectively.
conclusionThe study concluded that females are more affected by thyroid disorders than males and the peak age is at the forties, thyroid dysfunction affect all blood parameters except platelets.The follow up of patients with thyroid disorders should include the complete blood count and patients diagnosed with anemia should be evaluated for thyroid disorders before iron therapy. Cases of anemia that resist treatment should be investigated for the possibility of thyroid dysfunction.
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