Evidence map›Paper›PMID 32714498›Full record

ReviewInternational journal of molecular epidemiology and genetics2020

Exploring the usefulness of molecular epidemiology of tuberculosis in Africa: a systematic review.

Bourahima Kone, Anou M Somboro, Jane L Holl, Bocar Baya, Antieme Acg Togo, Yeya Dit Sadio Sarro, Bassirou Diarra, Ousmane Kodio, Robert L Murphy, William Bishai and 2 more

Abstract readReview
In one paragraph

Review in International journal of molecular epidemiology and genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Spatial Distribution of Drug-ResistantPathogens (Basel, Switzerland) · 2023
    Article
  6. Molecular epidemiology and genetic diversity of Mycobacterium tuberculosis complex in referral health centers of Bamako, Mali: What is new?International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bourahima KoneUniversity Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB) Bamako, Mali.
Anou M SomboroUniversity Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB) Bamako, Mali.
Jane L HollUniversity of Chicago Illinois, USA.
Bocar BayaUniversity Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB) Bamako, Mali.
Antieme Acg TogoUniversity Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB) Bamako, Mali.
Yeya Dit Sadio SarroUniversity Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB) Bamako, Mali.
Bassirou DiarraUniversity Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB) Bamako, Mali.
Ousmane KodioUniversity Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB) Bamako, Mali.
Robert L MurphyInstitute for Global Health, Northwestern University Chicago, Illinois, USA.
William BishaiCenter for TB Research, Johns Hopkins University Baltimore, MD, USA.
Mamoudou MaigaUniversity Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB) Bamako, Mali.
Seydou DoumbiaUniversity Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB) Bamako, Mali.

Funding

Metabolic and Immune Consequences of Antibiotic-Related Microbiome Alterations during TB TreatmentR21AI148033 · NIAID · NORTHWESTERN UNIVERSITY · PI MAIGA, MAMOUDOU · 2019 to 2020
$440k
Clinical Evaluation of a New Highly Sensitive Multiplex qPCR for Detecting tuberculosis and Non-tuberculous MycobacteriaR03AI137674 · NIAID · NORTHWESTERN UNIVERSITY · PI MAIGA, MAMOUDOU · 2018 to 2019
$149k
NIAID NIH HHS R03 AI137674NIAID NIH HHS R21 AI148033
6 · The paper itself

Abstract

backgroundTuberculosis (TB) is caused by

methodsSearch tools (PubMed, Embase, Popline, OVID and Africa Wide Information) were employed to identify the relevant literature about prevalence, strain diversity, and geographic distribution of MTBC infection in Africa.

resultsA total of 59 articles from 739 citations met our inclusion criteria. Most articles reported about patients with presumptive pulmonary TB (73%), fewer reports were on retreatment and treatment failure cases (12%), and presumptive drug resistance cases (3%). Spoligotyping was the most used, alone in 21 studies and in parallel with either the Mycobacterial Interspersed Repetitive Units Variable Number of Tandem Repeats or the Restriction Fragment Length Polymorphism. Various TB lineages were observed across the African continent, with the originally European lineage 4 spotted in all countries studied.

conclusionTB molecular epidemiology tools have substantially improved our understanding of the MTBC circulating isolates, their evolution, and diversity in this highly endemic region of Africa. We found that only TB lineage 4 is present throughout all the continent and the clusters identified provides an extended insight into the disease transmission dynamics.

Indexed as

Africamolecular epidemiologyMycobacterium tuberculosis complex

Identifiers

PMID32714498
PMCPMC7373718

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.