Evidence map›Paper›PMID 32714409›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

Rhubarb-Aconite Decoction (RAD) Drug-Containing Serum Alleviated Endotoxin-Induced Oxidative Stress Injury and Inflammatory Response in Caco-2 Cells In Vitro.

Xiao-Hong Du, Qing-Jun Chen, Jian-Bo Song, Yan Xie, Yan Zhi, Ru-Ru Sun, Guo-Hui Liu, Xin Kang

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Xiao-Hong DuDepartment of Hepatobiliary Pancreatic Surgery, First Hospital Bethune of Jilin University, Changchun 130021, China.
Qing-Jun ChenDepartment of Emergency Medicine, Beijing Hepingli Hospital, Beijing 100013, China.
Jian-Bo SongDepartment of Emergency Medicine, Affiliated Zhongshan Hospital, Dalian University, Dalian 116001, China.
Yan XieOrgan Transplant Center, Tianjin First Central Hospital, Tianjin 300000, China.
Yan ZhiDepartment of Burns, The Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China.
Ru-Ru SunDepartment of Emergency Medicine, Beijing Hepingli Hospital, Beijing 100013, China.
Guo-Hui LiuDepartment of Emergency Medicine, The First Hospital of Jilin University, Changchun 130012, China.ORCID https://orcid.org/0000-0002-4766-9444
Xin KangDepartment of Emergency Medicine, Beijing Hepingli Hospital, Beijing 100013, China.ORCID https://orcid.org/0000-0002-6754-9802
Beijing Anding Hospital · CNAffiliated Zhongshan Hospital of Dalian University · CNFirst Bethune Hospital of Jilin University · CNJilin University · CNKunming Medical University · CNTianjin First Center Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rhubarb-Aconite Decoction (RAD), a famous Chinese medicine prescription, has been widely used for treating intestinal injury. However, the effect of RAD on intestinal epithelial cells is unclear. The aim of this study was to investigate the effects of RAD drug-containing serum on the oxidative stress injury and inflammatory response induced by endotoxin (ET) in Caco-2 cells in vitro. Lipid peroxide malondialdehyde (MDA), lactate dehydrogenase (LDH), caspase-11, tumor necrosis factor-

Identifiers

PMID32714409
PMCPMC7355342
OpenAlexW3040528056

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.