ArticleFrontiers in human neuroscience2020
Different Effects of 2 mA and 4 mA Transcranial Direct Current Stimulation on Muscle Activity and Torque in a Maximal Isokinetic Fatigue Task.
Article in Frontiers in human neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04760899 (Bilateral Cerebellar Transcranial Direct Current Stimulation), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Bilateral Cerebellar Transcranial Direct Current Stimulation (tDCS) for the Treatment of Sports-Related Post-Concussion Syndrome (SRPCS)
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- The influence of a single transcranial direct current stimulation session on physical fitness in healthy subjects: a systematic review.Experimental brain research · 2023Pooled it
- Acute effects of anodal transcranial direct current stimulation on maximal voluntary force, repeated maximal isometric contractions and corticospinal excitability in healthy young adults.European journal of applied physiology · 2026Trial
- Unlocking trunk potential after stroke: a novel approach combining transcranial direct current stimulation and core stability exercise: a randomized controlled trial.Journal of neuroengineering and rehabilitation · 2026Trial
- Trial
- Concomitant dual-site tDCS and dark chocolate improve cognitive and endurance performance following cognitive effort under hypoxia: a randomized controlled trial.Scientific reports · 2023Trial
- Robust enhancement of motor sequence learning with 4 mA transcranial electric stimulation.Brain stimulationTrial
- The Influence of Dual Source Cerebellar Transcranial Direct Current Stimulation on Muscle Fatigue.Journal of functional morphology and kinesiology · 2026Article
- Dose-response of tDCS effects on motor learning and cortical excitability: A preregistered study.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Lattice layout and optimizer effect analysis for generating optimal transcranial electrical stimulation (tES) montages through the metaheuristic L1L1 method.Frontiers in human neuroscience · 2024Article
- Effects of Bilateral Extracephalic Transcranial Direct Current Stimulation on Lower Limb Kinetics in Countermovement Jumps.International journal of environmental research and public health · 2023Article
- Effects of single session transcranial direct current stimulation on aerobic performance and one arm pull-down explosive force of professional rock climbers.Frontiers in physiology · 2023Article
- The challenges of post-COVID-19 fatigue research.Frontiers in psychology · 2023Article
- Effects of high-definition transcranial direct current stimulation on the cortical-muscular functional coupling and muscular activities of ankle dorsi-plantarflexion under running-induced fatigue.Frontiers in physiology · 2023Article
- Effects of Preceding Transcranial Direct Current Stimulation on Movement Velocity and EMG Signal during the Back Squat Exercise.Journal of clinical medicine · 2022Article
- High Estrogen Levels Cause Greater Leg Muscle Fatigability in Eumenorrheic Young Women after 4 mA Transcranial Direct Current Stimulation.Brain sciences · 2022Article
- Halo Sport Transcranial Direct Current Stimulation Improved Muscular Endurance Performance and Neuromuscular Efficiency During an Isometric Submaximal Fatiguing Elbow Flexion Task.Frontiers in human neuroscience · 2022Article
- Personal Protective Equipment Alters Leg Muscle Fatigability Independent of Transcranial Direct Current Stimulation: A Comparison with Pre-COVID-19 Pandemic Results.Brain sciences · 2021Article
- Post-COVID-19 Fatigue: Potential Contributing Factors.Brain sciences · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies investigating the effects of transcranial direct current stimulation (tDCS) on fatigue and muscle activity have elicited measurable improvements using stimulation intensities ≤2 mA and submaximal effort tasks. The purpose of this study was to determine the effects of 2 mA and 4 mA anodal tDCS over the primary motor cortex (M1) on performance fatigability and electromyographic (EMG) activity of the leg muscles during a maximal isokinetic task in healthy young adults. A double-blind, randomized, sham-controlled crossover study design was applied. Twenty-seven active young adults completed four sessions, each spaced by 5-8 days. During session 1, dominance was verified with isokinetic strength testing, and subjects were familiarized with the fatigue task (FT). The FT protocol included 40 continuous maximum isokinetic contractions of the knee extensors and flexors (120°/s, concentric/concentric). During Sessions 2-4, tDCS was applied for 20 min with one of three randomly assigned intensities (sham, 2 mA or 4 mA) and the FT was repeated. The anode and cathode of the tDCS device were placed over C3 and the contralateral supraorbital area, respectively. A wireless EMG system collected muscle activity during the FT. The 2 mA tDCS condition had significantly less torque (65.9 ± 32.7 Nm) during the FT than both the sham (68.4 ± 33.9 Nm,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.