Evidence map›Paper›PMID 32714125›Full record

ArticleSSRN2020

Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.

Benjamin Israelow, Eric Song, Tianyang Mao, Peiwen Lu, Amit Meir, Feimei Liu, Mia Madel Alfajaro, Jin Wei, Huiping Dong, Robert J Homer and 3 more

Abstract readPreprint
In one paragraph

Article in SSRN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Benjamin IsraelowDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Eric SongDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Tianyang MaoDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Peiwen LuDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Amit MeirDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA.
Feimei LiuDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Mia Madel AlfajaroDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Jin WeiDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Huiping DongDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Robert J HomerDepartment of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA.
Aaron RingDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Craig B WilenDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Akiko IwasakiDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9M
INTERDISCIPLINARY IMMUNOLOGY TRAINING PROGRAMT32AI007019 · NIAID · YALE UNIVERSITY · PI Carrie L. Lucas, David G. Schatz · 1985 to 2026
$14.4M
TRAINING IN THE PATHOGENESIS OF INFECTIOUS DISEASEST32AI007517 · NIAID · YALE UNIVERSITY · PI Jaimie Meyer, Albert C Shaw · 1997 to 2026
$6.1M
Immunity to Genital Herpes Simplex-2R01AI054359 · NIAID · YALE UNIVERSITY · PI IWASAKI, AKIKO · 2004 to 2019
$5.2M
B cell based protection against recurrent herpesR01AI127429 · NIAID · YALE UNIVERSITY · PI IWASAKI, AKIKO · 2017 to 2021
$2.1M
Role of virus-receptor interactions in determining norovirus tropism and pathogenesis in vivoK08AI128043 · NIAID · YALE UNIVERSITY · PI WILEN, CRAIG BRIAN · 2017 to 2021
$940k
Meningeal lymphangiogenesis effect on malignancy ofglioblastoma.F30CA239444 · NCI · YALE UNIVERSITY · PI SONG, HOYEON ERIC · 2019 to 2021
$111k
NCATS NIH HHS UL1 TR001863NCI NIH HHS F30 CA239444NIAID NIH HHS K08 AI128043NIAID NIH HHS R01 AI054359NIAID NIH HHS R01 AI127429NIAID NIH HHS T32 AI007019NIAID NIH HHS T32 AI007517NIGMS NIH HHS T32 GM007205
6 · The paper itself

Abstract

Severe Acute Respiratory Syndrome- Coronavirus 2 (SARS-Cov-2) has caused over 5,000,000 cases of Coronavirus disease (COVID-19) with significant fatality rate.

Identifiers

PMID32714125
PMCPMC7366812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.