Evidence map›Paper›PMID 32714104›Full record

ArticleSSRN2020

Candidate Targets for Immune Responses to 2019-Novel Coronavirus (nCoV): Sequence Homology- and Bioinformatic-Based Predictions.

Alba Grifoni, John Sidney, Yun Zhang, Richard H Scheuermann, Bjoern Peters, Alessandro Sette

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in SSRN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Alba GrifoniDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
John SidneyDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Yun ZhangJ. Craig Venter Institute, La Jolla, CA 92037, USA.
Richard H ScheuermannDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Bjoern PetersDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Alessandro SetteDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.

Funding

IMMUNE EPITOPE AND ANALYSIS PROGRAM: Transplantation of organs, tissues and cells 75N93019C00001 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI WILSON, STEPHEN · 2019 to 2025
$23.1M
NIAID NIH HHS 75N93019C00001
6 · The paper itself

Abstract

Effective countermeasures against the recent emergence and rapid expansion of the 2019-Novel Coronavirus (2019-nCoV) require the development of data and tools to understand and monitor viral spread and immune responses. However, little information about the targets of immune responses to 2019-nCoV is available. We used the Immune Epitope Database and Analysis Resource (IEDB) resource to catalog available data related to other coronaviruses, including SARS-CoV, which has high sequence similarity to 2019-nCoV, and is the best-characterized coronavirus in terms of epitope responses. We identified multiple specific regions in 2019-nCoV that have high homology to SARS virus. Parallel bionformatic predictions identified

Indexed as

2019-nCoVB cell epitopecoronavirusCOVID-19infectious diseaseSARS-CoVsequence conservationT cell epitope

Identifiers

PMID32714104
PMCPMC7366807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.