Evidence map›Paper›PMID 32714026›Full record

ArticleSaudi journal of biological sciences2020

Association between HindIII (rs320) variant in the lipoprotein lipase gene and the presence of coronary artery disease and stroke among the Saudi population.

Neda M Bogari, Ashwag Aljohani, Anas Dannoun, Osama Elkhateeb, Masimo Porqueddu, Amr A Amin, Dema N Bogari, Mohiuddin M Taher, Faruk Buba, Reem M Allam and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Saudi journal of biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 6 countries.

Neda M BogariDepartment of Medical Genetics, Faculty of Medicine, Umm Al-Qura University (UQU), Saudi Arabia.
Ashwag AljohaniDepartment of Medical Genetics, Faculty of Medicine, Umm Al-Qura University (UQU), Saudi Arabia.
Anas DannounDepartment of Medical Genetics, Faculty of Medicine, Umm Al-Qura University (UQU), Saudi Arabia.
Osama ElkhateebDepartment of Cardiology, King Abdulla Medical city, Makkah, Saudi Arabia.
Masimo PorquedduDepartment of Cardiac Surgery, King Fahd Armed Medical Forces Hospitals, Jeddah, KSA, Saudi Arabia.
Amr A AminBiochemistry Department, Faculty of medicine, UQU, Saudi Arabia.
Dema N BogariBiomedical Sciences, University of Brighton, England, UK.
Mohiuddin M TaherDepartment of Medical Genetics, Faculty of Medicine, Umm Al-Qura University (UQU), Saudi Arabia.
Faruk BubaDepartment of Internal Medicine, College of Medical Sciences, University of Maiduguri, Nigeria.
Reem M AllamClinical Pathology Department, Faculty of Medicine, Zagazig University, Egypt.
Mustafa N BogariSchool of Pharmacy, University of Brighton, England, UK.
Francesco AlamanniDepartment of Cardiac Surgery, Monzino Heart Center, University of Milan, Milan, Italy.
Umm al-Qura University · SAUniversity of Brighton · GBAin Shams University · EGCentro Cardiologico Monzino · ITKing Abdullah Medical City · SAUniversity of Maiduguri · NGUniversity of Milan · ITZagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipoprotein Lipase (LPL) is known to be a key enzyme for lipid metabolism specifically in an enzymatic glycoprotein which provide tissues without fatty-acids and eliminates triglycerides (TG) by the circulation. Mutations in LPL were proven to cause alteration in fractions within lipoprotein, causing the development of atherosclerosis which predispose to weakening coronary artery disease (CAD) and stroke. We examined the linkage between genetic variant

Indexed as

Coronary artery diseaseLipoprotein lipaseRs320 and HindIIIStroke

Identifiers

PMID32714026
PMCPMC7376116
OpenAlexW3037338940

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.